| MP:0000013 | abnormal fat distribution | "alterations in the normal placement and amount of body fat" [J:57315] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000189 | hypoglycemia | "low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000192 | abnormal mineral level | "anomalous concentration of any inorganic substance that has importance in body functions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000274 | enlarged heart | "increase over normal size of the heart" [J:29971] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000416 | sparse fur | "fur that is significantly less dense" [J:46854] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0000639 | abnormal adrenal gland morphology | "malformed endocrine glands located above the kidney responsible for hormone and epinephrine secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61190] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0000947 | convulsive seizures | "seizures characterized by uncontrolled motor activity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0001199 | thin skin | "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001242 | hyperkeratosis | "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001244 | thin dermal layer | "reduced thickness of the dermis" [J:65030] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0001433 | polyphagia | "eating to excess" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0001560 | abnormal circulating insulin level | "anomalous blood concentration of this polypeptide hormone, secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0001654 | hepatic necrosis | "pathologic death of cells within, or a portion of, the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001745 | increased circulating corticosterone level | "greater than the normal concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:54931] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001943 | abnormal respiration | "anomaly in the movement of gases into and out of the lung " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002078 | abnormal glucose homeostasis | "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002127 | abnormal cardiovascular system morphology | "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002163 | abnormal gland morphology | "abnormal development of any glandular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
|
| MP:0002286 | cryptorchism | "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002696 | decreased circulating glucagon level | "lower than normal blood concentration of this peptide hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0002837 | dystrophic cardiac calcinosis | "a condition characterized by the localized deposition of calcium salts in the heart; often occuring in association with inflammation or atherosclerotic lesions and other pathological states" [J:76777, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0003643 | spleen atrophy | "wasting of the spleen resulting in reduced size" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0003717 | pallor | "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0005129 | increased adrenocorticotropin level | "increased concentration of adrenocorticotropic hormone " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0005215 | abnormal islet of Langerhans morphology | "anomalous morphology of these structures that are scattered throughout the pancreas and comprise its endocrine portion; within each islet there are three cell types: alpha, beta, and delta " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0005243 | hemothorax | "bleeding into the pleural space" [Pathology:ISBN 0-397-51047-0] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0005491 | islet cell hyperplasia | "increased numbers cells within the structures that are scattered throughout the pancreas and comprise its endocrine portion" [J:48446, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0005534 | decreased body temperature | "less than the level of heat natural to a living being" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0008299 | adrenal cortical hyperplasia | "overdevelopment of the thick outer layer of the adrenal gland that produces and secretes steroid hormones, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0008321 | small adenohypophysis | "reduced size of the anterior part of the pituitary that secretes a variety of hormones" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0009113 | increased pancreatic beta cell mass | "greater total physical bulk or volume of a pancreatic beta cell compared to the normal state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0009275 | bruising | "an injury to biological tissue in which the capillaries are damaged, allowing blood to seep into the surrounding tissue; it should not be confused with ecchymosis, though the terms are related" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0009276 | ecchymosis | "an ecchymosis is a spot caused by loss of blood from a vessel; it implies a larger size than a petechiae, and has a more diffuse border than purpura; an ecchymosis can be caused by a bruise (which implies trauma), but can also be caused by bleeding diathesis" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0010093 | decreased circulating magnesium level | "a reduction in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0010400 | increased liver glycogen level | "greater than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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| MP:0013405 | increased circulating lactate level | "greater amount of lactate in the blood which is produced from pyruvate by lactate dehydrogenase" [MPD:Molly] |
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Allelic Composition: Shroom3Gt(ROSA53)Sor/Shroom3+
Genetic Background: involves: 129S4/SvJaeSor
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