ENSMUSG00000023452


Mus musculus

Features
Gene ID: ENSMUSG00000023452
  
Biological name :Pisd
  
Synonyms : phosphatidylserine decarboxylase / Pisd / Q8BSF4
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B1
Gene start: 32736301
Gene end: 32785646
  
Corresponding Affymetrix probe sets: 10529239 (MoGene1.0st)   1426387_x_at (Mouse Genome 430 2.0 Array)   1460585_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112573
Ensembl peptide - ENSMUSP00000144616
Ensembl peptide - ENSMUSP00000143277
Ensembl peptide - ENSMUSP00000142818
Ensembl peptide - ENSMUSP00000122705
Ensembl peptide - ENSMUSP00000120201
Ensembl peptide - ENSMUSP00000119621
Ensembl peptide - ENSMUSP00000051438
Ensembl peptide - ENSMUSP00000071732
NCBI entrez gene - 320951     See in Manteia.
MGI - MGI:2445114
RefSeq - XM_017320930
RefSeq - NM_001347332
RefSeq - NM_177298
RefSeq - XM_006503999
RefSeq - XM_006504000
RefSeq - XM_006504002
RefSeq - XM_017320929
RefSeq Peptide - NP_796272
RefSeq Peptide - NP_001334261
swissprot - Q505E1
swissprot - D3Z0X7
swissprot - D3YY63
swissprot - A0A0G2JFR5
swissprot - A0A0G2JEL6
swissprot - F7C386
swissprot - Q8BSF4
swissprot - D6RIN9
swissprot - E9PX91
Ensembl - ENSMUSG00000023452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pisdENSDARG00000052462Danio rerio
 PISDENSGALG00000006872Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm20671ENSMUSG0000009357491


Protein motifs (from Interpro)
Interpro ID Name
 IPR003817  Phosphatidylserine decarboxylase-related
 IPR033177  Phosphatidylserine decarboxylase
 IPR033661  Phosphatidylserine decarboxylase, eukaryotic type 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0016540 protein autoprocessing IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IEA
 molecular_functionGO:0004609 phosphatidylserine decarboxylase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001674 abnormal triploblastic development "abnormal development of the three primary germ layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

 MP:0013241 embryo tissue necrosis "morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage" [MGI:csmith]
Show

Allelic Composition: Apoetm1(APOE)Sfu/Apoetm1(APOE)Sfu
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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