ENSMUSG00000023926


Mus musculus

Features
Gene ID: ENSMUSG00000023926
  
Biological name :Rhag
  
Synonyms : Ammonium transporter Rh type A / Q9QUT0 / Rhag
  
Possible biological names infered from orthology : Q02094 / Rh associated glycoprotein
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B2
Gene start: 40811126
Gene end: 40840754
  
Corresponding Affymetrix probe sets: 10445192 (MoGene1.0st)   1419014_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024721
NCBI entrez gene - 19743     See in Manteia.
MGI - MGI:1202713
RefSeq - XM_006523913
RefSeq - NM_011269
RefSeq - XM_006523912
RefSeq Peptide - NP_035399
swissprot - Q9QUT0
Ensembl - ENSMUSG00000023926
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhagENSDARG00000019253Danio rerio
 RHAGENSGALG00000016684Gallus gallus
 RHAGENSG00000112077Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rhcg / Q9QXP0 / Ammonium transporter Rh type C / Q9UBD6* / Rh family C glycoprotein*ENSMUSG0000003054948
Rhbg / Q8BUX5 / Ammonium transporter Rh type B / Q9H310* / Rh family B glycoprotein (gene/pseudogene)*ENSMUSG0000010444547
Gm38392 / RHBG* / Q9H310* / Rh family B glycoprotein (gene/pseudogene)*ENSMUSG0000010376644
Rhd / RHCE* / P18577* / Q02161* / Rh blood group D antigen* / Rh blood group CcEe antigens*ENSMUSG0000002882531


Protein motifs (from Interpro)
Interpro ID Name
 IPR002229  Blood group Rhesus C/E/D polypeptide
 IPR024041  Ammonium transporter AmtB-like domain
 IPR029020  Ammonium/urea transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006873 cellular ion homeostasis IEA
 biological_processGO:0015670 carbon dioxide transport IEA
 biological_processGO:0015672 monovalent inorganic cation transport IEA
 biological_processGO:0015695 organic cation transport IBA
 biological_processGO:0015696 ammonium transport ISO
 biological_processGO:0048821 erythrocyte development IMP
 biological_processGO:0060586 multicellular organismal iron ion homeostasis IMP
 biological_processGO:0072488 ammonium transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008519 ammonium transmembrane transporter activity ISO
 molecular_functionGO:0022840 leak channel activity IEA
 molecular_functionGO:0030506 ankyrin binding IEA


Pathways (from Reactome)
Pathway description
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Rhesus glycoproteins mediate ammonium transport.


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003656 abnormal erythrocyte physiology "functional anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata/Gt(ROSA)26Sor+,Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata/Gt(ROSA)26Sor+,Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata/Gt(ROSA)26Sor+,Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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