ENSMUSG00000024146


Mus musculus

Features
Gene ID: ENSMUSG00000024146
  
Biological name :Cript
  
Synonyms : Cript / Cysteine-rich PDZ-binding protein / O70333
  
Possible biological names infered from orthology : CXXC repeat containing interactor of PDZ3 domain / Q9P021
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: E4
Gene start: 87025550
Gene end: 87035810
  
Corresponding Affymetrix probe sets: 10447349 (MoGene1.0st)   1423486_at (Mouse Genome 430 2.0 Array)   1423487_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024959
Ensembl peptide - ENSMUSP00000124994
NCBI entrez gene - 56724     See in Manteia.
MGI - MGI:1929655
RefSeq - NM_019936
RefSeq Peptide - NP_064320
swissprot - F6TQQ9
swissprot - O70333
Ensembl - ENSMUSG00000024146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 criptENSDARG00000102511Danio rerio
 CRIPTENSGALG00000010014Gallus gallus
 CRIPTENSG00000119878Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019367  PDZ-binding protein, CRIPT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031122 cytoplasmic microtubule organization IEA
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:1902897 regulation of postsynaptic density protein 95 clustering IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0043198 dendritic shaft IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0044877 protein-containing complex binding ISS
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6+
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
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Allelic Composition: Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove/Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove
Genetic Background: FVB/N-Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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