ENSMUSG00000024391


Mus musculus

Features
Gene ID: ENSMUSG00000024391
  
Biological name :Apom
  
Synonyms : Apolipoprotein M / Apom / Q9Z1R3
  
Possible biological names infered from orthology : O95445
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 35128997
Gene end: 35132050
  
Corresponding Affymetrix probe sets: 10450444 (MoGene1.0st)   1419095_a_at (Mouse Genome 430 2.0 Array)   1419096_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025249
NCBI entrez gene - 55938     See in Manteia.
MGI - MGI:1930124
RefSeq - NM_018816
RefSeq Peptide - NP_061286
swissprot - Q9Z1R3
Ensembl - ENSMUSG00000024391
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apomENSDARG00000076838Danio rerio
 APOMENSG00000204444Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012674  Calycin
 IPR022734  Apolipoprotein M


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0033344 cholesterol efflux IEA
 biological_processGO:0034375 high-density lipoprotein particle remodeling IEA
 biological_processGO:0034380 high-density lipoprotein particle assembly IMP
 biological_processGO:0034384 high-density lipoprotein particle clearance IMP
 biological_processGO:0034445 negative regulation of plasma lipoprotein oxidation IDA
 biological_processGO:0042157 lipoprotein metabolic process IMP
 biological_processGO:0043691 reverse cholesterol transport IMP
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IEA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0034364 high-density lipoprotein particle IDA
 cellular_componentGO:0034365 discoidal high-density lipoprotein particle IDA
 cellular_componentGO:0034366 spherical high-density lipoprotein particle IEA
 molecular_functionGO:0005319 lipid transporter activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding ISS
 molecular_functionGO:0016209 antioxidant activity IDA


Pathways (from Reactome)
Pathway description
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ighmtm4Bgmn/Ighmtm4Bgmn
Genetic Background: involves: 129/Sv

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Emx1tm1(cre)Yql/Emx1+,Tor1atm2Yql/Tor1atm2Yql
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

 MP:0003983 decreased cholesterol level "less than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Emx1tm1(cre)Yql/Emx1+,Tor1atm2Yql/Tor1atm2Yql
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0004906 enlarged uterus 
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Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

 MP:0004931 enlarged epididymis "increase in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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