ENSMUSG00000024622


Mus musculus

Features
Gene ID: ENSMUSG00000024622
  
Biological name :Hmgxb3
  
Synonyms : HMG domain-containing protein 3 isoform 1 / Hmgxb3
  
Possible biological names infered from orthology : HMG-box containing 3 / Q12766
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E1
Gene start: 61131279
Gene end: 61177050
  
Corresponding Affymetrix probe sets: 10459158 (MoGene1.0st)   1418044_at (Mouse Genome 430 2.0 Array)   1443950_at (Mouse Genome 430 2.0 Array)   1457653_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000089498
NCBI entrez gene - 106894     See in Manteia.
MGI - MGI:2441817
RefSeq - XM_017317779
RefSeq - NM_134134
RefSeq - NM_178277
RefSeq Peptide - NP_598895
RefSeq Peptide - NP_840061
swissprot - G3X9M3
Ensembl - ENSMUSG00000024622
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmgxb3ENSDARG00000077823Danio rerio
 HMGXB3ENSGALG00000005770Gallus gallus
 HMGXB3ENSG00000113716Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000026 abnormal inner ear morphology "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0003686 abnormal eye muscle morphology "malformation of the muscles of the eye" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0004269 abnormal optic cup morphology "any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0004463 basisphenoid bone foramen "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0006063 abnormal inferior vena cava morphology "structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013834 thin hypoglossal nerve "slender appearance of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013835 absent hypoglossal nerve "absence of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013836 abnormal hypoglossal nerve topology "abnormal position of the hypoglossal nerve " [MGI:csmith]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013848 subcutaneous edema "accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013876 absent ductus venosus valve "absence of the valve present on the right side of the ductus venosus at the site of the junction with the inferior vena cava" [PMID:5438957]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013877 abnormal ductus venosus valve morphology "any structural anomaly of the valve present on the right side of the ductus venosus at the site of the junction with the inferior vena cava" [PMID:5438957]
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

 MP:0013971 blood in lymph vessels 
Show

Allelic Composition: Fustm1Emcf/Fus+
Genetic Background: involves: C3H * C57BL/6J * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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