ENSMUSG00000024725


Mus musculus

Features
Gene ID: ENSMUSG00000024725
  
Biological name :Ostf1
  
Synonyms : Osteoclast-stimulating factor 1 / Ostf1 / Q62422
  
Possible biological names infered from orthology : Q92882
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: B
Gene start: 18579328
Gene end: 18631789
  
Corresponding Affymetrix probe sets: 10466573 (MoGene1.0st)   1446023_at (Mouse Genome 430 2.0 Array)   1452246_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025631
NCBI entrez gene - 20409     See in Manteia.
MGI - MGI:700012
RefSeq - NM_017375
RefSeq Peptide - NP_059071
swissprot - Q62422
Ensembl - ENSMUSG00000024725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ostf1ENSDARG00000091555Danio rerio
 OSTF1ENSGALG00000017447Gallus gallus
 OSTF1ENSG00000134996Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036028  SH3-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0013615 increased volumetric bone mineral density "increase in the mineral mass per unit volume of bone, the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts; this is expressed as the amount of mineral per cubic cm of bone (usually in mgHA/cm^3), with results generated from Quantitative computed tomography (QCT) and other tests" [PMID:12730800, PMID:17481978]
Show

Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0020011 increased bone mineral density of femur "elevation in the amount of mineral per square centimeter of bone (usually g/cm2) in the long bone of the thigh" [GOC:NV]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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