Manteia

ENSMUSG00000024736

Mus musculus

Features

Gene ID:	ENSMUSG00000024736

Biological name :	Tmem132a

Synonyms :	Q922P8 / Tmem132a / Transmembrane protein 132A

Possible biological names infered from orthology :	Q24JP5

Species:	Mus musculus

Chr. number:	19
Strand:	-1
Band:	A
Gene start:	10857822
Gene end:	10869940

Corresponding Affymetrix probe sets:	10466075 (MoGene1.0st) 1416845_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000113696 Ensembl peptide - ENSMUSP00000025645 NCBI entrez gene - 98170 See in Manteia. MGI - MGI:2147810 RefSeq - NM_133804 RefSeq - XM_006527503 RefSeq Peptide - NP_598565 swissprot - D3Z4S6 swissprot - Q922P8 Ensembl - ENSMUSG00000024736

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
	ENSGALG00000031067	Gallus gallus
Q24JP5	ENSG00000006118	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q6IEE6 / Tmem132e / transmembrane protein 132E / Q6IEE7*	ENSMUSG00000020701	33
Tmem132c / transmembrane protein 132C / Q8N3T6*	ENSMUSG00000034324	33
Tmem132b / transmembrane protein 132B / Q14DG7*	ENSMUSG00000070498	32
Tmem132d / transmembrane protein 132D / Q14C87*	ENSMUSG00000034310	31

Protein motifs (from Interpro)

Interpro ID	Name
IPR026307	Transmembrane protein 132
IPR031435	Transmembrane protein TMEM132, N-terminal
IPR031436	Transmembrane protein TMEM132, C-terminal
IPR031437	Transmembrane protein family 132, middle domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
cellular_component	GO:0000139	Golgi membrane	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IBA
cellular_component	GO:0005789	endoplasmic reticulum membrane	IEA
cellular_component	GO:0005794	Golgi apparatus	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IBA
molecular_function	GO:0003674	molecular_function	ND

Pathways (from Reactome)

Pathway description

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Post-translational protein phosphorylation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000428	abnormal craniofacial morphology	"anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0000438	abnormal skull morphology	"anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0000564	syndactyly	"any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0001697	abnormal embryo size	"anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0002109	abnormal limb morphology	"abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0002111	abnormal tail morphology	"abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0003054	spina bifida	"common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0003720	abnormal neural tube closure	"abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0003743	abnormal facial morphology	"anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0003795	abnormal bone structure		Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0005650	abnormal limb bud morphology	"aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0010024	increased total body fat amount	"greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics
MP:0011495	abnormal head shape	"any anomaly in the characteristic surface outline or contour of a head of an organism" [MGI:csmith]	Show Allelic Composition: Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺ Genetic Background: C57BL/6N-Thra^{tm1b(EUCOMM)Wtsi}/Ics

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr