ENSMUSG00000024787


Mus musculus

Features
Gene ID: ENSMUSG00000024787
  
Biological name :Snx15
  
Synonyms : Q91WE1 / Snx15 / Sorting nexin-15
  
Possible biological names infered from orthology : Q9NRS6
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 6119399
Gene end: 6128304
  
Corresponding Affymetrix probe sets: 10465379 (MoGene1.0st)   1424337_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114189
Ensembl peptide - ENSMUSP00000122740
Ensembl peptide - ENSMUSP00000025702
NCBI entrez gene - 69024     See in Manteia.
MGI - MGI:1916274
RefSeq - XM_006531831
RefSeq - XM_011248650
RefSeq - XM_011248651
RefSeq - NM_026912
RefSeq Peptide - NP_081188
swissprot - Q91WE1
swissprot - D3YVT2
swissprot - D3Z479
Ensembl - ENSMUSG00000024787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx15ENSDARG00000020397Danio rerio
 SNX15ENSG00000110025Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BLK9 / Rps6kc1 / ribosomal protein S6 kinase polypeptide 1 / Q96S38* / ribosomal protein S6 kinase C1*ENSMUSG0000008987215
Q8R2S1 / Rps6kl1 / ribosomal protein S6 kinase-like 1 / Q9Y6S9*ENSMUSG0000001923515


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR007330  MIT
 IPR035048  Sorting nexin-15
 IPR036181  MIT domain superfamily
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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