ENSMUSG00000024903


Mus musculus

Features
Gene ID: ENSMUSG00000024903
  
Biological name :Lao1
  
Synonyms : L-amino acid oxidase 1 / Lao1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.1
Gene start: 118961578
Gene end: 118968912
  
Corresponding Affymetrix probe sets: 10507580 (MoGene1.0st)   1417650_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062834
NCBI entrez gene - 100470     See in Manteia.
MGI - MGI:2140628
RefSeq - NM_133892
RefSeq Peptide - NP_598653
swissprot - B1ARV3
Ensembl - ENSMUSG00000024903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL4I1ENSDARG00000056804Danio rerio
 IL4I1ENSGALG00000000081Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
4930438A08Rik / RIKEN cDNA 4930438A08 geneENSMUSG0000006987353
Il4i1 / interleukin 4 induced 1 / Q96RQ9*ENSMUSG0000007414138


Protein motifs (from Interpro)
Interpro ID Name
 IPR001613  Flavin amine oxidase
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009063 cellular amino acid catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0001716 L-amino-acid oxidase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0004047 abnormal milk composition "anomaly in the protein or lipid content of milk" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008751 abnormal interleukin level "deviation from the normal levels of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0013148 mastitis "inflammation of the teats or mammary glands" [MGI:Ahmad_Retha]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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