ENSMUSG00000024903


Mus musculus

Features
Gene ID: ENSMUSG00000024903
  
Biological name :Lao1
  
Synonyms : L-amino acid oxidase 1 / Lao1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.1
Gene start: 118961578
Gene end: 118968912
  
Corresponding Affymetrix probe sets: 10507580 (MoGene1.0st)   1417650_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062834
NCBI entrez gene - 100470     See in Manteia.
MGI - MGI:2140628
RefSeq - NM_133892
RefSeq Peptide - NP_598653
swissprot - B1ARV3
Ensembl - ENSMUSG00000024903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL4I1ENSDARG00000056804Danio rerio
 IL4I1ENSGALG00000000081Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
4930438A08Rik / RIKEN cDNA 4930438A08 geneENSMUSG0000006987353
Il4i1 / interleukin 4 induced 1 / Q96RQ9*ENSMUSG0000007414138


Protein motifs (from Interpro)
Interpro ID Name
 IPR001613  Flavin amine oxidase
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009063 cellular amino acid catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0001716 L-amino-acid oxidase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0004047 abnormal milk composition "anomaly in the protein or lipid content of milk" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008751 abnormal interleukin level "deviation from the normal levels of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0013148 mastitis "inflammation of the teats or mammary glands" [MGI:Ahmad_Retha]
Show

Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr