ENSMUSG00000025157


Mus musculus

Features
Gene ID: ENSMUSG00000025157
  
Biological name :Zdhhc16
  
Synonyms : Q9ESG8 / Zdhhc16 / zinc finger, DHHC domain containing 16
  
Possible biological names infered from orthology : Q969W1 / zinc finger DHHC-type containing 16
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 41933480
Gene end: 41944104
  
Corresponding Affymetrix probe sets: 10463173 (MoGene1.0st)   1421115_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026154
Ensembl peptide - ENSMUSP00000153672
Ensembl peptide - ENSMUSP00000153627
Ensembl peptide - ENSMUSP00000153604
Ensembl peptide - ENSMUSP00000153513
Ensembl peptide - ENSMUSP00000152902
Ensembl peptide - ENSMUSP00000152899
NCBI entrez gene - 74168     See in Manteia.
MGI - MGI:1921418
RefSeq - XM_017318300
RefSeq - NM_023740
RefSeq - XM_006527403
RefSeq - XM_006527404
RefSeq - XM_006527406
RefSeq - XM_006527407
RefSeq Peptide - NP_076229
swissprot - Q9ESG8
swissprot - A0A286YDX9
swissprot - A0A286YDP1
swissprot - A0A286YCB6
swissprot - A0A286YCB5
swissprot - A0A286YED0
swissprot - A0A286YDY5
Ensembl - ENSMUSG00000025157
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B8A4F0ENSDARG00000007808Danio rerio
 zdhhc16bENSDARG00000015989Danio rerio
 ZDHHC16ENSGALG00000007592Gallus gallus
 Q969W1ENSG00000171307Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CPV7 / Zdhhc6 / zinc finger, DHHC domain containing 6 / Q9H6R6* / zinc finger DHHC-type containing 6*ENSMUSG0000002498223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001594  Palmitoyltransferase, DHHC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0018345 protein palmitoylation IEA
 biological_processGO:0021537 telencephalon development ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016409 palmitoyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0019706 protein-cysteine S-palmitoyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0001286 abnormal eye development "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

Allelic Composition: Plntm1Egk/Plntm1Egk,Zdhhc16tm1Goff/Zdhhc16tm1Goff
Genetic Background: involves: 129S1/Sv * 129S2/SvPas

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0002058 neonatal lethality "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0003393 decreased cardiac output "reduction in the blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0004090 abnormal sarcomere morphology "any structural abnormality in the segment of a myofibril between two Z lines comprised of multi-protein complexes composed of three different filament systems; these systems work together to contract and relax muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0005330 cardiomyopathy "diseases of the heart (myocardium); may result from many causes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80681]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0008772 enlarged heart ventricle "increased average size of the heart ventricles compared to the average for a particular population" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0008788 abnormal fetal cardiomyocyte morphology "any structural anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [PMID:17429040]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Plntm1Egk/Plntm1Egk,Zdhhc16tm1Goff/Zdhhc16tm1Goff
Genetic Background: involves: 129S1/Sv * 129S2/SvPas

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

 MP:0011952 decreased cardiac stroke volume "reduction in the volume of blood pushed into the aorta with each beat of the heart" [MGI:csmith]
Show

Allelic Composition: Pcdha9em1Clo/Pcdha9em1Clo,Sap130em1Clo/Sap130em1Clo
Genetic Background: C57BL/6J-Sap130em1Clo Pcdha9em1Clo/MurrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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