ENSMUSG00000025468


Mus musculus

Features
Gene ID: ENSMUSG00000025468
  
Biological name :Caly
  
Synonyms : Caly / Neuron-specific vesicular protein calcyon / Q9DCA7
  
Possible biological names infered from orthology : calcyon neuron specific vesicular protein / Q9NYX4
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F4
Gene start: 140069880
Gene end: 140082548
  
Corresponding Affymetrix probe sets: 10568921 (MoGene1.0st)   1428813_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026541
Ensembl peptide - ENSMUSP00000130779
Ensembl peptide - ENSMUSP00000148159
Ensembl peptide - ENSMUSP00000148173
NCBI entrez gene - 68566     See in Manteia.
MGI - MGI:1915816
RefSeq - XM_011249853
RefSeq - NM_001190385
RefSeq - NM_001190386
RefSeq - NM_026769
RefSeq - XM_006536235
RefSeq - XM_006536236
RefSeq - XM_006536237
RefSeq Peptide - NP_001177314
RefSeq Peptide - NP_001177315
RefSeq Peptide - NP_081045
swissprot - Q9DCA7
Ensembl - ENSMUSG00000025468
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CALYENSG00000130643Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nsg1 / Q62092 / Neuronal vesicle trafficking-associated protein 1 / P42857* / neuronal vesicle trafficking associated 1*ENSMUSG0000002912625
Nsg2 / P47759 / neuron specific gene family member 2 / Q9Y328* / neuronal vesicle trafficking associated 2*ENSMUSG0000002029720


Protein motifs (from Interpro)
Interpro ID Name
 IPR009431  Neuronal vesicle trafficking-associated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0016197 endosomal transport IBA
 biological_processGO:0045807 positive regulation of endocytosis ISO
 biological_processGO:0048268 clathrin coat assembly ISS
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 molecular_functionGO:0032051 clathrin light chain binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001899 absent long term depression "lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdx1tm3Lhn/Cdx1tm3Lhn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdx1tm3Lhn/Cdx1tm3Lhn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0004770 abnormal synaptic vesicle recycling "any functional anomaly in the process of the fusion of a subpopulation of synaptic vesicles with the cell membrane at the active zone, the subsequent endocytosis back from the plasma membrane, the refilling of these vesicles with neurotransmitters, and trafficking back to the active zone pool of vesicles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdx1tm3Lhn/Cdx1tm3Lhn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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