ENSMUSG00000025609


Mus musculus

Features
Gene ID: ENSMUSG00000025609
  
Biological name :Mkln1
  
Synonyms : Mkln1 / Muskelin / O89050
  
Possible biological names infered from orthology : muskelin 1 / Q9UL63
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A3.3
Gene start: 31398735
Gene end: 31516811
  
Corresponding Affymetrix probe sets: 10537078 (MoGene1.0st)   1416733_at (Mouse Genome 430 2.0 Array)   1416734_at (Mouse Genome 430 2.0 Array)   1436096_at (Mouse Genome 430 2.0 Array)   1446203_at (Mouse Genome 430 2.0 Array)   1458919_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026699
Ensembl peptide - ENSMUSP00000123048
NCBI entrez gene - 27418     See in Manteia.
MGI - MGI:1351638
RefSeq - XM_017321606
RefSeq - NM_013791
RefSeq - XM_017321605
RefSeq Peptide - NP_038819
swissprot - O89050
swissprot - F6UW85
Ensembl - ENSMUSG00000025609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mkln1ENSDARG00000025576Danio rerio
 MKLN1ENSGALG00000006356Gallus gallus
 MKLN1ENSG00000128585Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006594  LIS1 homology motif
 IPR006595  CTLH, C-terminal LisH motif
 IPR006652  Kelch repeat type 1
 IPR008979  Galactose-binding-like domain superfamily
 IPR010565  Muskelin, N-terminal
 IPR011043  Galactose oxidase/kelch, beta-propeller
 IPR015915  Kelch-type beta propeller
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0031532 actin cytoskeleton reorganization IMP
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000371 diluted coat color "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cav1tm1.1Aia/Cav1tm1.1Aia,Rxfp2tm1Aia/Rxfp2+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB

 MP:0003245 abnormal GABA neuron morphology "malformation or absence of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cav1tm1.1Aia/Cav1tm1.1Aia,Rxfp2tm1Aia/Rxfp2+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB

 MP:0003633 abnormal nervous system physiology 
Show

Allelic Composition: Cav1tm1.1Aia/Cav1tm1.1Aia,Rxfp2tm1Aia/Rxfp2+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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