ENSMUSG00000025658


Mus musculus

Features
Gene ID: ENSMUSG00000025658
  
Biological name :Ksr2
  
Synonyms : connector enhancer of kinase suppressor of Ras 2 / Ksr2 / Q80YA9
  
Possible biological names infered from orthology : CNKSR2 / Q8WXI2
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F4
Gene start: 157821436
Gene end: 158043294
  
Corresponding Affymetrix probe sets: 10607562 (MoGene1.0st)   1444513_at (Mouse Genome 430 2.0 Array)   1445194_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026750
Ensembl peptide - ENSMUSP00000108132
NCBI entrez gene - 245684     See in Manteia.
MGI - MGI:2661175
RefSeq - XM_017318508
RefSeq - NM_001310719
RefSeq - NM_177751
RefSeq - XM_006528861
RefSeq - XM_011247826
RefSeq - XM_017318507
RefSeq Peptide - NP_001297648
RefSeq Peptide - NP_808419
swissprot - A2AI78
swissprot - Q80YA9
Ensembl - ENSMUSG00000025658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnksr2aENSDARG00000074480Danio rerio
 cnksr2bENSDARG00000073707Danio rerio
 ENSGALG00000016391Gallus gallus
 ENSGALG00000033942Gallus gallus
 CNKSR2ENSG00000149970Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Magi1 / Q8BMA3 / Cnksr family member 3 / Q8WWN9* / IPCEF1* / Q6P9H4* / CNKSR3* / interaction protein for cytohesin exchange factors 1*ENSMUSG0000001520230
Cnksr1 / connector enhancer of kinase suppressor of Ras 1 / Q969H4*ENSMUSG0000002884122
Ipcef1 / Q5DU31 / Mus musculus interaction protein for cytohesin exchange factors 1 (Ipcef1), transcript variant 5, mRNA. / Q8WWN9* / Q6P9H4* / CNKSR3* / CNKSR family member 3* / interactio...ENSMUSG0000006406515
Gm45194ENSMUSG0000010915612


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001660  Sterile alpha motif domain
 IPR001849  Pleckstrin homology domain
 IPR010599  Connector enhancer of kinase suppressor of ras 2
 IPR011993  PH-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR017874  CRIC domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
MAP2K and MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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