ENSMUSG00000026017


Mus musculus

Features
Gene ID: ENSMUSG00000026017
  
Biological name :Carf
  
Synonyms : Calcium-responsive transcription factor / Carf / Q8VHI4
  
Possible biological names infered from orthology : Q8N187
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C2
Gene start: 60098247
Gene end: 60153953
  
Corresponding Affymetrix probe sets: 10346678 (MoGene1.0st)   1425313_at (Mouse Genome 430 2.0 Array)   1460588_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137867
Ensembl peptide - ENSMUSP00000137825
Ensembl peptide - ENSMUSP00000139554
Ensembl peptide - ENSMUSP00000141169
Ensembl peptide - ENSMUSP00000139878
Ensembl peptide - ENSMUSP00000027171
Ensembl peptide - ENSMUSP00000121293
NCBI entrez gene - 241066     See in Manteia.
MGI - MGI:2182269
RefSeq - XM_017320612
RefSeq - XM_011238510
RefSeq - XM_017320594
RefSeq - XM_017320597
RefSeq - XM_017320598
RefSeq - XM_017320599
RefSeq - XM_017320602
RefSeq - XM_017320604
RefSeq - XM_017320606
RefSeq - XM_017320609
RefSeq - NM_001285463
RefSeq - NM_001285473
RefSeq - NM_139150
RefSeq - XM_006495974
RefSeq - XM_006495975
RefSeq - XM_006495977
RefSeq Peptide - NP_001272402
RefSeq Peptide - NP_631889
RefSeq Peptide - NP_001272392
swissprot - A8VI08
swissprot - D3Z2W4
swissprot - Q8VHI4
swissprot - A0A087WPQ8
swissprot - A8VI09
swissprot - M0QWJ8
Ensembl - ENSMUSG00000026017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 carfENSDARG00000019950Danio rerio
 CARFENSGALG00000008474Gallus gallus
 CARFENSG00000138380Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029309  Calcium-responsive transcription factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0035865 cellular response to potassium ion ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion ISO
 biological_processGO:0071277 cellular response to calcium ion ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001458 abnormal object recognition memory "defects in the ability to recognize objects that the animal has previously encountered; recognition is measured by relative amount of time exploring objects, which should decrease upon subsequent or multiple presentations of the same object when presented with novel objects at the same time" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0002800 abnormal short-term recognition memory "defects in the short-term memory for objects is established during the first few minutes after training" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0008414 abnormal spatial reference memory "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0009454 impaired contextual conditioning "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0010570 prolonged ST segment "increase in the length of time between the end of S-wave and the beginning of T-wave; reflects the amount of time the ventricles remain electrically depolarized" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cacna1btm1b(KOMP)Wtsi/Cacna1btm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cacna1btm1b(KOMP)Wtsi/H

 MP:0011953 prolonged PQ interval "increase in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave" [MPD:Molly]
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Allelic Composition: Cacna1btm1b(KOMP)Wtsi/Cacna1btm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cacna1btm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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