ENSMUSG00000026102


Mus musculus

Features
Gene ID: ENSMUSG00000026102
  
Biological name :Inpp1
  
Synonyms : Inositol polyphosphate 1-phosphatase / Inpp1 / P49442
  
Possible biological names infered from orthology : P49441
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C1.1
Gene start: 52785427
Gene end: 52817688
  
Corresponding Affymetrix probe sets: 10354521 (MoGene1.0st)   1418045_at (Mouse Genome 430 2.0 Array)   1442073_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135225
Ensembl peptide - ENSMUSP00000027271
Ensembl peptide - ENSMUSP00000123977
Ensembl peptide - ENSMUSP00000124890
NCBI entrez gene - 16329     See in Manteia.
MGI - MGI:104848
RefSeq - XM_011238442
RefSeq - NM_008384
RefSeq - XM_011238441
RefSeq Peptide - NP_032410
swissprot - E0CX64
swissprot - P49442
swissprot - H3BK26
swissprot - E0CYQ4
Ensembl - ENSMUSG00000026102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-160o17.2ENSDARG00000002897Danio rerio
 INPP1ENSG00000151689Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000760  Inositol monophosphatase-like
 IPR020550  Inositol monophosphatase, conserved site
 IPR020583  Inositol monophosphatase, metal-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 molecular_functionGO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP2, IP, and Ins in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Hdac8tm1a(EUCOMM)Wtsi/Hdac8tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Hdac8tm1a(EUCOMM)Wtsi/Wtsi

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Hdac8tm1a(EUCOMM)Wtsi/Hdac8tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Hdac8tm1a(EUCOMM)Wtsi/Wtsi

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Hdac8tm1a(EUCOMM)Wtsi/Hdac8tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Hdac8tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kat14tm1a(KOMP)Wtsi/Kat14tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Hdac8tm1a(EUCOMM)Wtsi/Hdac8tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Hdac8tm1a(EUCOMM)Wtsi/Wtsi

 MP:0010168 increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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