ENSMUSG00000026171


Mus musculus

Features
Gene ID: ENSMUSG00000026171
  
Biological name :Rnf25
  
Synonyms : E3 ubiquitin-protein ligase RNF25 / Q9QZR0 / Rnf25
  
Possible biological names infered from orthology : Q96BH1 / ring finger protein 25
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C3
Gene start: 74593748
Gene end: 74601397
  
Corresponding Affymetrix probe sets: 10355628 (MoGene1.0st)   1448674_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115350
Ensembl peptide - ENSMUSP00000138040
Ensembl peptide - ENSMUSP00000120646
Ensembl peptide - ENSMUSP00000117692
Ensembl peptide - ENSMUSP00000116973
Ensembl peptide - ENSMUSP00000027357
Ensembl peptide - ENSMUSP00000109350
NCBI entrez gene - 57751     See in Manteia.
MGI - MGI:1890215
RefSeq - XM_006496170
RefSeq - NM_001305230
RefSeq - NM_021313
RefSeq Peptide - NP_001292159
RefSeq Peptide - NP_067288
swissprot - D3Z7S2
swissprot - Q9QZR0
swissprot - E9Q446
swissprot - D3Z0R9
swissprot - F6Z123
swissprot - D3YXC4
swissprot - M0QWW2
Ensembl - ENSMUSG00000026171
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf25ENSDARG00000027182Danio rerio
 RNF25ENSGALG00000011375Gallus gallus
 RNF25ENSG00000163481Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR006575  RWD domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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