ENSMUSG00000026344


Mus musculus

Features
Gene ID: ENSMUSG00000026344
  
Biological name :Lypd1
  
Synonyms : Ly6/PLAUR domain-containing protein 1 / Lypd1 / Q8BLC3
  
Possible biological names infered from orthology : LY6/PLAUR domain containing 1 / Q8N2G4
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E3
Gene start: 125867622
Gene end: 125913101
  
Corresponding Affymetrix probe sets: 10357339 (MoGene1.0st)   1431569_a_at (Mouse Genome 430 2.0 Array)   1442887_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123824
Ensembl peptide - ENSMUSP00000125149
Ensembl peptide - ENSMUSP00000125158
Ensembl peptide - ENSMUSP00000027582
Ensembl peptide - ENSMUSP00000124265
NCBI entrez gene - 72585     See in Manteia.
MGI - MGI:1919835
RefSeq - XM_017312443
RefSeq - NM_001311089
RefSeq - NM_001311090
RefSeq - NM_145100
RefSeq - XM_006529885
RefSeq - XM_011248088
RefSeq Peptide - NP_001298019
RefSeq Peptide - NP_659568
RefSeq Peptide - NP_001298018
swissprot - F6TKE8
swissprot - Q8BLC3
swissprot - E0CXP0
Ensembl - ENSMUSG00000026344
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LYPD1ENSGALG00000012176Gallus gallus
 LYPD1ENSG00000150551Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IMP
 biological_processGO:0001775 cell activation IBA
 biological_processGO:0007271 synaptic transmission, cholinergic IDA
 biological_processGO:0035094 response to nicotine IMP
 biological_processGO:0095500 acetylcholine receptor signaling pathway IDA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IDA
 biological_processGO:2000272 negative regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030550 acetylcholine receptor inhibitor activity IMP
 molecular_functionGO:0033130 acetylcholine receptor binding IPI


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001454 abnormal cued conditioning behavior "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002799 abnormal passive avoidance behavior "defects in the ability of an animal to enter an hostile environment where it receives a unpleasant or punishing stimuli applied previously with prolonged latency" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002910 abnormal excitatory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003459 increased fear-related response "greater emotional response related to anticipation of specific pain or danger" [CFG:Center for Functional Genomics, Northwestern University]
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Allelic Composition: Mecp2tm2.1Jae/Y
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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