ENSMUSG00000026347


Mus musculus

Features
Gene ID: ENSMUSG00000026347
  
Biological name :Tmem163
  
Synonyms : Q8C996 / Tmem163 / Transmembrane protein 163
  
Possible biological names infered from orthology : Q8TC26
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E3
Gene start: 127486546
Gene end: 127679548
  
Corresponding Affymetrix probe sets: 10357371 (MoGene1.0st)   1428077_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027585
Ensembl peptide - ENSMUSP00000124307
Ensembl peptide - ENSMUSP00000140828
NCBI entrez gene - 72160     See in Manteia.
MGI - MGI:1919410
RefSeq - XM_017312413
RefSeq - NM_028135
RefSeq - XM_011248087
RefSeq Peptide - NP_082411
swissprot - Q8C996
Ensembl - ENSMUSG00000026347
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem163aENSDARG00000079858Danio rerio
 tmem163bENSDARG00000088227Danio rerio
 TMEM163ENSGALG00000012190Gallus gallus
 Q8TC26ENSG00000152128Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026765  Transmembrane protein 163
 IPR027469  Cation efflux transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IDA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane ISS
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0008270 zinc ion binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000008 increased white fat amount "increased quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000133 abnormal long bone metaphysis morphology "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0000149 abnormal scapula morphology "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
Show

Allelic Composition: Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000154 rib fusion "appearance of one or more ribs as a single structure" [J:62022, J:62023]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000163 abnormal cartilage morphology "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Srgap3tm1.1Ssod/Srgap3+,Tg(Thy1-EGFP)#Jrs/0
Genetic Background: involves: C57BL/6J * CBA

 MP:0000164 abnormal cartilage development "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Srgap3tm1.1Ssod/Srgap3+,Tg(Thy1-EGFP)#Jrs/0
Genetic Background: involves: C57BL/6J * CBA

 MP:0000373 belly spot "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Dct-LacZ)A12Jkn/Tg(Dct-LacZ)A12Jkn
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA * FVB/N

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0000440 domed skull 
Show

Allelic Composition: Pthlhtm1Hmk/Pthlh+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0000627 abnormal mammary gland morphology "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183]
Show

Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000690 absent spleen "missing organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:55583]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000709 enlarged thymus "increased size of thymus" [J:50053]
Show

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0000783 abnormal forebrain morphology "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Gdf7tm2Tmj/Gdf7+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Lhx2tm1Dra/Lhx2tm1Dra
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000913 abnormal brain development "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]
Show

Allelic Composition: Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Hesx1tm1(cre)Jpmb/Hesx1tm1(cre)Jpmb
Genetic Background: B6.129S-Hesx1tm1(cre)Jpmb

Allelic Composition: Gt(ROSA)26Sortm1(Hesx1)Jpmb/Gt(ROSA)26Sortm1(Hesx1)Jpmb,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Gdf7tm2Tmj/Gdf7+,Tg(Hsp70-1-cre)6Arge/0
Genetic Background: involves: 129S1/Sv * C57BL/6J * CBA

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

Allelic Composition: Grem1tm1Ecan/Grem1+,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0000934 abnormal telencephalon development "malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]
Show

Allelic Composition: Lhx2tm1Dra/Lhx2tm1Dra
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001121 uterine hypoplasia "reduced size of the uterus due to decreased cell number" [J:45065]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001126 abnormal ovary morphology "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001129 impaired ovarian folliculogenesis "a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001134 absent corpora lutea "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001159 absent prostate gland "missing gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66126]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001261 obese "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Cd79atm2Cgn/Cd79atm2Cgn
Genetic Background: involves: C57BL/6 * C.B-20

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Dct-LacZ)A12Jkn/Tg(Dct-LacZ)A12Jkn
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA * FVB/N

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pthlhtm1Hmk/Pthlh+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Tg(KRT14-Figf)1Ali/0,Vegfctm1Ali/Vegfc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB

 MP:0001328 disorganized retinal layers "delaminated or mispositioned sheets of cells comprising the optic part of the retina" [J:33400]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sortm1(Rybp/EGFP)Cve,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,En1tm2(cre)Wrst/En1+,Tg(ACTFLPe)9205Dym/0
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001382 abnormal nursing "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Arntltm1.1Ljm/Arntltm1.1Ljm,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: C57BL/6 * FVB/N

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001625 cardiac hypertrophy "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0001688 abnormal somite development "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

 MP:0001764 abnormal homeostasis "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001882 abnormal lactation "atypical production of milk from the mammary gland" [J:51296]
Show

Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scarb1Hdlq1-129S1/SvImJ/?
Genetic Background: involves: 129S1/SvImJ * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0001940 testicular hypoplasia "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001951 abnormal breathing "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0001956 hypopnea "breathing that is shallower and/or slower than normal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:64289]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0002016 ovarian cysts "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * BALB/c * C57BL/6

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prnptm2Lnq/Prnptm2Lnq
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srgap3tm1.1Ssod/Srgap3+,Tg(Thy1-EGFP)#Jrs/0
Genetic Background: involves: C57BL/6J * CBA

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pawrtm1Yshi/Pawrtm1Yshi,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB/N

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002286 cryptorchism "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002669 abnormal scrotum morphology "malformation of the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0002699 abnormal vitreous body "anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sortm1(Rybp/EGFP)Cve,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0002780 decreased circulating testosterone level "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002781 increased circulating testosterone level "greater than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0002784 abnormal Sertoli cell morphology "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003008 enhanced long term potentiation "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0003055 abnormal epiphyseal plate morphology "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0003124 hypospadia "a urethral opening located closer to the base of the penis and not at the tip" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003234 enhanced NMDA-mediated synaptic currents "increase in the measured amplitude or duration of response to stimulation of NMDA receptors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0003400 kinked neural tube "twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0003409 decreased width of hypertrophic chondrocyte zone "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

 MP:0003417 premature endochondral bone ossification "early onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0003557 absent vas deferens "absence of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003607 abnormal prostate physiology "malfunction of the gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0003642 absent seminal gland "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003662 abnormal proliferative zone "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd79atm2Cgn/Cd79atm2Cgn
Genetic Background: involves: C57BL/6 * C.B-20

 MP:0004077 abnormal striatum morphology "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Myh4arl/Myh4arl
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0004101 abnormal brain interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the brain; this includes most brain neuronal cell types" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myh4arl/Myh4arl
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0004218 meiotic nondisjunction during M1 phase "abnormal separation of pairs of homologous chromosomes during anaphase of the first meiotic division such that each daughter cell receives one set of paired chromosomes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0004344 scapular bone hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, in either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0004353 abnormal deltoid tuberosity morphology "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0004672 short ribs "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0004727 absent epididymis "absence of the elongated structure connected to the posterior surface of the testis, consisting of the head, body, and tail, which turns sharply on itself to become the ductus deferens (vas deferens)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004734 small thoracic cavity "reduced size of the cavity in the vertebrate body enclosed by the ribcage between the diaphragm and the neck, and contains the lungs, heart, thoracic aorta, pulmonary artery and its branches, thymus gland, and the respiratory airway" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004893 decreased adiponectin level "reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0004905 decreased uterus weight "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005188 small penis "in comparison to the norm, reduced size of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005189 abnormal anogenital distance "in comparison to the norm, aberration in the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005205 abnormal eye anterior chamber "anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sortm1(Rybp/EGFP)Cve,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0005262 coloboma "anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sortm1(Rybp/EGFP)Cve,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0005288 abnormal oxygen consumption "deviation from the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005296 abnormal humerus morphology "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pbx1tm1.1Koss/Pbx1tm1.2Koss,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0005317 increased triglyceride level "higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005331 insulin resistance "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0005455 increased weight gain "greater increase in body weight over existing weight when compared to the average increase in weight on the same diet, with equal energy (calorie) intake " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:42702]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

 MP:0005542 corneal vascularization "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sortm1(Rybp/EGFP)Cve,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(Rybp/EGFP)Cve/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005575 increased pulmonary ventilation "greater than the normal total volume of gas per minute inspired or expired " [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0005585 increased tidal volume "greater than the normal volume of air inspired or expired during each normal respiratory cycle" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006281 abnormal tail development "anomaly in the formation of the tail" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0006295 absent sclerotome "absence of the group of mesenchymal cells that emerge from the ventromedial part of a somite and migrate toward the notochord to give rise to the ribs and vertebrae" [J:60303, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0006378 abnormal spermatogonia morphology "anomaly in the number, structure or development of the large unspecialized male germ cells that give rise to spermatocytes" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006386 absent somites "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Braftm1Mmcm/Braf+,Tg(Tg-cre/ERT2)#Mmcm/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0006397 disorganized long bone epiphyseal plate "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

 MP:0008256 abnormal myometrium morphology "any structural anomaly of the smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium" [MESH:A02.633.570.500, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Tex11tm1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008868 abnormal granulosa cell morphology "any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0008934 absent choroid plexus "absence of the fringe of the tela choroidea of the brain ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Gdf7tm2Tmj/Gdf7+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0008966 abnormal chiasmata formation "atypical contact between nonsister chromatids of homologous chromosomes during meiosis I, precluding formation of the expected number of cross-shaped configurations representing recombination events" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Tex11tm1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008984 vagina hypoplasia "underdevelopment or reduced size of the vagina, usually due to a reduced number of cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0009066 decreased oviduct weight "reduction in the average weight of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009115 abnormal fat cell morphology "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0009199 abnormal external male genitalia morphology "any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009204 absent external male genitalia "absence of the external masculine genital organs, including the penis and scrotum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009285 increased gonadal fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009302 increased renal fat pad weight 
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009361 abnormal primordial ovarian follicle morphology "any structural abnormality in the ovarian follicle in which the primary oocyte is surrounded by a single layer of flattened follicular cells; primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0009362 abnormal primary ovarian follicle morphology "any structural abnormality in the ovarian follicle prior to the appearance of an antrum, normally marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0009453 enhanced contextual conditioning "increase in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0009736 abnormal prostate gland branching morphogenesis "anomaly of the prostatic bud to repeatedly divide into lobules during development of the prostate gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Fev-flpe)1Dym/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0009908 protruding tongue "the tongue extends out beyond the oral cavity past the lips; may be due to paralysis, oral cavity size, tongue hypoplasia or dysfunction of the hypoglossal nerve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1Syeh/Esr1tm1Syeh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129X1/SvJ * FVB/N

 MP:0010734 abnormal paranode morphology "any structural anomaly of the axon region immediately adjacent to nodes of Ranvier, where a series of cytoplasmic loops from the overlying glial cell form septate-like junctions with the axon; the axoglial junctions act as a diffusion barrier between the node and internode" [PMID:16224497]
Show

Allelic Composition: Nfasctm2Bhat/Nfasctm2Bhat,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Epb41l3tm1Bhat/Epb41l3tm1.1Bhat,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: FVB/N

 MP:0010735 abnormal paranodal axoglial junction morphology "any structural anomaly of the structure in which the myelin sheath attaches to the axon at each end of each myelin segment; the axoglial junctions act as a diffusion barrier between the node and internode, maintaining domain-specific axolemmal membrane components" [PMID:19224642]
Show

Allelic Composition: Epb41l3tm1Bhat/Epb41l3tm1.1Bhat,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: FVB/N

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Pthlhtm1Ack/Pthlhtm1Hmk,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129 * BALB/c * FVB/N

Allelic Composition: Pthlhtm1Ack/Pthlhtm1.1Ack,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Braftm1Mmcm/Braf+,Tg(Tg-cre/ERT2)#Mmcm/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Cd79atm2Cgn/Cd79atm2Cgn
Genetic Background: involves: C57BL/6 * C.B-20

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Aifm1tm2Pngr/Aifm1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N

 MP:0011620 abnormal habituation to a new environment "anomaly in the process in which there is a progressive decline of behavioral response probability with an exposure to a new environment" [MGI:csmith]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011732 decreased somite size "reduced size of any of the segmental masses along the notochord of the developing embryo" [MGI:smb]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

Allelic Composition: Grem1tm1Ecan/Grem1+,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0011925 abnormal heart echocardiography feature "any anomaly in echocardiographic representation of systolic and diastolic function, ventricular compliance, valvular function, or interventricular septum features" [MPD:Molly]
Show

Allelic Composition: Braftm1Mmcm/Braf+,Tg(Tg-cre/ERT2)#Mmcm/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0012023 decreased melanocyte number "reduced number of the cells that produce pigment" [MGI:llw2]
Show

Allelic Composition: Raph1tm1.1Makr/Raph1tm1.1Makr,Tmem163Tg(ACTB-cre)2Mrt/0,Tg(Dct-LacZ)A12Jkn/Tg(Dct-LacZ)A12Jkn
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA * FVB/N

 MP:0012176 abnormal head development "anomaly in the process in which the anatomical structures of the head are generated and organized" [GO:0060323]
Show

Allelic Composition: Grem1tm1Ecan/Grem1tm1Ecan,Nogtm1.1Rmh/Nogtm1.1Rmh,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
Show

Allelic Composition: Tcf4tm1Hmb/Tcf4+,Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0012724 failure of head fold formation "inability to form the crescent-shaped, ventrally located fold of the embryonic disc at the future cephalic end of the developing embryo; the head fold constitutes the first body fold, and initiates brain, foregut and heart development" [MGI:anna]
Show

Allelic Composition: Braftm1Mmcm/Braf+,Tg(Tg-cre/ERT2)#Mmcm/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0013598 Leydig cell hypertrophy "increased size of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH)" [MGI:Anna]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0020039 increased bone ossification "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0020467 abnormal circadian behavior "any anomaly in the specific behavior of an organism that recurs with a regularity of approximately 24 hours" [GO:0048512]
Show

Allelic Composition: Arntltm1.1Ljm/Arntltm1.1Ljm,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr