ENSMUSG00000026511


Mus musculus

Features
Gene ID: ENSMUSG00000026511
  
Biological name :Srp9
  
Synonyms : P49962 / signal recognition particle 9 / Srp9
  
Possible biological names infered from orthology : P49458
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H5
Gene start: 182124737
Gene end: 182132407
  
Corresponding Affymetrix probe sets: 10352393 (MoGene1.0st)   10473547 (MoGene1.0st)   1417530_a_at (Mouse Genome 430 2.0 Array)   1448753_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106647
Ensembl peptide - ENSMUSP00000027792
NCBI entrez gene - 27058     See in Manteia.
MGI - MGI:1350930
RefSeq - NM_012058
RefSeq Peptide - NP_036188
swissprot - D3YZX8
swissprot - P49962
swissprot - Q5EAT0
Ensembl - ENSMUSG00000026511
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srp9ENSDARG00000042851Danio rerio
 SRP9ENSGALG00000026009Gallus gallus
 SRP9ENSG00000143742Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008832  Signal recognition particle, SRP9 subunit
 IPR009018  Signal recognition particle, SRP9/SRP14 subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane IEA
 biological_processGO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation IBA
 biological_processGO:0045900 negative regulation of translational elongation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005785 signal recognition particle receptor complex IBA
 cellular_componentGO:0005786 signal recognition particle, endoplasmic reticulum targeting IBA
 cellular_componentGO:0048500 signal recognition particle IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005047 signal recognition particle binding IBA
 molecular_functionGO:0008312 7S RNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0003019 increased circulating chloride level "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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