ENSMUSG00000026617


Mus musculus

Features
Gene ID: ENSMUSG00000026617
  
Biological name :Bpnt1
  
Synonyms : 3(2),5-bisphosphate nucleotidase 1 / Bpnt1 / Q9Z0S1
  
Possible biological names infered from orthology : O95861
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H5
Gene start: 185332149
Gene end: 185357777
  
Corresponding Affymetrix probe sets: 10352503 (MoGene1.0st)   1418764_a_at (Mouse Genome 430 2.0 Array)   1449211_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117122
Ensembl peptide - ENSMUSP00000147674
Ensembl peptide - ENSMUSP00000027916
Ensembl peptide - ENSMUSP00000106590
NCBI entrez gene - 23827     See in Manteia.
MGI - MGI:1338800
RefSeq - XM_006497162
RefSeq - NM_011794
RefSeq - XM_006497159
RefSeq - XM_006497160
RefSeq - XM_006497161
RefSeq Peptide - NP_035924
RefSeq Peptide - NP_001334141
RefSeq Peptide - NP_001334139
swissprot - A0A1B0GRV0
swissprot - D3Z5X0
swissprot - Q9Z0S1
swissprot - D3Z0E6
Ensembl - ENSMUSG00000026617
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bpnt1ENSDARG00000043684Danio rerio
 BPNT1ENSGALG00000009576Gallus gallus
 BPNT1ENSG00000162813Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Impad1 / Q80V26 / Inositol monophosphatase 3 / Q9NX62* / inositol monophosphatase domain containing 1*ENSMUSG0000006632426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000760  Inositol monophosphatase-like
 IPR020550  Inositol monophosphatase, conserved site
 IPR020583  Inositol monophosphatase, metal-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 molecular_functionGO:0008441 3"(2"),5"-bisphosphate nucleotidase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cytosolic sulfonation of small molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0000603 pale liver "liver lacking normal coloration, often refers to bloodless condition" [J:18048]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0000607 abnormal hepatocyte morphology "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0001570 abnormal circulating enzyme level "aberrent concentration in the blood of any of the proteins that act as catalysts for biological reactions" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0002941 increased circulating alanine transaminase level "increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0003983 decreased cholesterol level "less than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0005416 abnormal circulating protein level "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0010332 abnormal circulating apolipoprotein level "anomaly in the amount in the blood of a protein that is frequently a component of a lipoprotein complex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0010333 abnormal circulating apolipoprotein E level "anomaly in the amount in the blood of a protein that is frequently a component of a VLDL, HDL, and chylomicron complexes, and functions in cholesterol transport" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

 MP:0011738 anasarca "widespread swelling due to effusion of serous fluid into the extracellular space, especially into the connective tissue" [MGI:smb]
Show

Allelic Composition: Impad1Gt(RST634)Byg/Impad1Gt(RST634)Byg,Papss2bm/Papss2bm
Genetic Background: involves: 129P2/OlaHsd * LDJ/Le

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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