ENSMUSG00000026676


Mus musculus

Features
Gene ID: ENSMUSG00000026676
  
Biological name :Ccdc3
  
Synonyms : Ccdc3 / Coiled-coil domain-containing protein 3 / Q9D6Y1
  
Possible biological names infered from orthology : coiled-coil domain containing 3 / Q9BQI4
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A1
Gene start: 5137776
Gene end: 5230878
  
Corresponding Affymetrix probe sets: 10469066 (MoGene1.0st)   1428549_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027988
NCBI entrez gene - 74186     See in Manteia.
MGI - MGI:1921436
RefSeq - NM_028804
RefSeq Peptide - NP_083080
swissprot - Q9D6Y1
Ensembl - ENSMUSG00000026676
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccdc3aENSDARG00000026052Danio rerio
 CCDC3ENSGALG00000030140Gallus gallus
 CCDC3ENSG00000151468Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IDA
 biological_processGO:0046889 positive regulation of lipid biosynthetic process IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002310 resistance to fatty liver development "less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002891 increased insulin sensitivity "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0005334 abnormal fat pad "malformed or aberrant size of the encapsulated adipose tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0005668 decreased circulating leptin level "less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009133 decreased white fat cell size "reduction in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009356 decreased liver triglyceride level "lower than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Klf2tm1Hhn/Klf2tm1Hhn
Genetic Background: involves: 129S4/SvJae * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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