ENSMUSG00000026807


Mus musculus

Features
Gene ID: ENSMUSG00000026807
  
Biological name :Ak8
  
Synonyms : Adenylate kinase 8 / Ak8 / Q32M07
  
Possible biological names infered from orthology : Q96MA6
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 28700164
Gene end: 28813165
  
Corresponding Affymetrix probe sets: 10470614 (MoGene1.0st)   1428628_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073789
NCBI entrez gene - 68870     See in Manteia.
MGI - MGI:1916120
RefSeq - XM_017319245
RefSeq - NM_001033874
RefSeq - XM_006498292
RefSeq - XM_017319244
RefSeq - XM_006498287
RefSeq - XM_006498288
RefSeq - XM_006498289
RefSeq - XM_006498291
RefSeq Peptide - NP_001029046
swissprot - Q32M07
Ensembl - ENSMUSG00000026807
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak8ENSDARG00000030961Danio rerio
 AK8ENSGALG00000040923Gallus gallus
 AK8ENSG00000165695Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ak2 / Q9WTP6 / Adenylate kinase 2, mitochondrial / P54819* / adenylate kinase 2*ENSMUSG0000002879211


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036193  Adenylate kinase, active site lid domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0009142 nucleoside triphosphate biosynthetic process IEA
 biological_processGO:0009165 nucleotide biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0021591 ventricular system development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0036126 sperm flagellum IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity ISO
 molecular_functionGO:0004127 cytidylate kinase activity IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0019206 nucleoside kinase activity ISO


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000825 dilated lateral ventricles "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857]
Show

Allelic Composition: Stk36tm1Lex/Stk36tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Stk36tm1Lex/Stk36tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0008283 small hippocampus "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Stk36tm1Lex/Stk36tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr