| MP:0000277 | abnormal heart shape | "malformation of the form or the patterning of the heart" [J:18048] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0000278 | abnormal myocardial fiber morphology | "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0001544 | abnormal cardiovascular system physiology | "anomalous function of the blood, blood vessels, and/or the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
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| MP:0002190 | disorganized myocardium | "malformed or poorly developed cardiac muscle layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67044] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0002833 | increased heart weight | "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
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| MP:0002834 | decreased heart weight | "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0003222 | increased cardiomyocyte apoptosis | "increase in the number of cardiac muscle cells undergoing programmed cell death" [RGD:Rat Genome Database submission] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0003402 | decreased liver weight | "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0003638 | abnormal response/metabolism to endogenous compounds | "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
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| MP:0003717 | pallor | "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0003920 | abnormal right ventricle morphology | "structural anomaly of the right lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0004011 | decreased diastolic filling velocity | "reduction in the rate of fluid inflow to the heart during diastole compared to controls; usually measured in the left ventricle; altered filling velocity often contributes to various cardiovascular disorders" [RGD:Rat Genome Database submission] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0004067 | abnormal ventricular trabeculae morphology | "aberrant structure of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0004564 | enlarged myocardial fiber | "increased size of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
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| MP:0004565 | small myocardial fiber | "decreased size of the cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0006267 | abnormal intercalated disc morphology | "any structural abnormality in the electron dense junctional complex, at the end to end contacts of cardiac muscle cells, that contains two types of membrane junctions i.e. gap junctions and desmosomes" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:64280] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0009674 | decreased birth weight | "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0010420 | muscular ventricular septal defect | "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0010640 | ventricular myocardium compact layer hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the ventricular portion of the outer, dense layer of the myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: A/?,Lystbg/Lystbg,Tyrp1+/?
Genetic Background: Not Specified
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