ENSMUSG00000027108


Mus musculus

Features
Gene ID: ENSMUSG00000027108
  
Biological name :Ola1
  
Synonyms : Obg-like ATPase 1 / Ola1 / Q9CZ30
  
Possible biological names infered from orthology : Q9NTK5
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C3
Gene start: 73092801
Gene end: 73218924
  
Corresponding Affymetrix probe sets: 10483648 (MoGene1.0st)   1430053_a_at (Mouse Genome 430 2.0 Array)   1432151_at (Mouse Genome 430 2.0 Array)   1438094_x_at (Mouse Genome 430 2.0 Array)   1460391_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107686
Ensembl peptide - ENSMUSP00000028517
Ensembl peptide - ENSMUSP00000097592
NCBI entrez gene - 67059     See in Manteia.
MGI - MGI:1914309
RefSeq - NM_025942
RefSeq - NM_030091
RefSeq Peptide - NP_080218
RefSeq Peptide - NP_084367
swissprot - B1AYJ9
swissprot - Q9CZ30
Ensembl - ENSMUSG00000027108
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ola1ENSDARG00000044565Danio rerio
 OLA1ENSGALG00000009325Gallus gallus
 OLA1ENSG00000138430Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004396  Ribosome-binding ATPase YchF/Obg-like ATPase 1
 IPR006073  GTP binding domain
 IPR012675  Beta-grasp domain superfamily
 IPR012676  TGS-like
 IPR013029  YchF, C-terminal domain
 IPR023192  TGS-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031167  OBG-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046034 ATP metabolic process ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000597 delayed hepatic development "late onset of the induction and/or differentiation of the liver" [J:18048]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Lepob/Lepob,Mogat1tm1Far/Mogat1tm1Far
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Lepob/Lepob,Mogat1tm1Far/Mogat1tm1Far
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0002058 neonatal lethality "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0011024 abnormal branching involved in lung morphogenesis "anomaly in the process in which the branched structure of the respiratory airway tree is generated and organized" [MGI:csmith]
Show

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Lepob/Lepob,Mogat1tm1Far/Mogat1tm1Far
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Ola1Gt(OST312288)Lex/Ola1Gt(OST312288)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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