| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000219 | increased neutrophil count | "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000223 | decreased monocyte count | "fewer than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000552 | abnormal radius morphology | "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0001539 | decreased number of caudal vertebrae | "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0003047 | abnormal thoracic vertebrae morphology | "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0004599 | abnormal vertebral arch morphology | "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005011 | increased eosinophil count | "greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005015 | increased T cell number | "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005017 | decreased B cell number | "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005270 | abnormal zygomatic bone morphology | "anomalous structure of the bone that forms the prominence of the cheek" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0005298 | abnormal clavicle morphology | "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0008045 | decreased NK cell number | "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0008074 | increased CD4-positive T cell number | "greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0008078 | increased CD8-positive T cell number | "greater number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0008211 | decreased mature B cell number | "reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0008347 | decreased gamma-delta T cell number | "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0010099 | abnormal thoracic cage shape | "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0010168 | increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | "a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0012764 | increased alpha-beta T cell number | "greater number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0012768 | decreased KLRG1-positive NK cell number | "decrease in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation" [MGI:Annie_Speak, PMID:19479342] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013022 | increased Ly6C high monocyte number | "increase in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues" [MGI:Annie_Speak] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013026 | decreased Ly6C low monocyte number | "decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes" [MGI:Annie_Speak] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013294 | prenatal lethality prior to heart atrial septation | "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013417 | decreased memory-marker gamma-delta T cell number | "reduction in the number of memory-marker gamma-delta T cells with a CD44+ CD62L- phenotype" [IMPC:Saran, PMID:23928962] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013418 | increased memory-marker gamma-delta T cell number | "increase in the number of memory-marker gamma-delta T cells with a CD44+ CD62L- phenotype" [IMPC:Saran, PMID:23928962] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013429 | decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number | "reduction in the number of the CD4+, CD25+ alpha-beta regulatory T cells with a CD44+ CD62L- memory phenotype" [IMPC:Saran] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013436 | increased CD8-positive, naive alpha-beta T cell number | "increase in the number of the naïve regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions with a CD44-low CD62L+ phenotype" [IMPC:Saran] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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| MP:0013771 | decreased effector memory T-helper cell number | "reduction in the number of CD4-positive alpha-beta T-helper cells with a CD44-positive, CD62L-negative memory phenotype" [MGI:Saran] |
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl
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