ENSMUSG00000027306


Mus musculus

Features
Gene ID: ENSMUSG00000027306
  
Biological name :Nusap1
  
Synonyms : Nucleolar and spindle-associated protein 1 / Nusap1 / Q9ERH4
  
Possible biological names infered from orthology : Q9BXS6
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 119618298
Gene end: 119651244
  
Corresponding Affymetrix probe sets: 10474984 (MoGene1.0st)   10474998 (MoGene1.0st)   1416309_at (Mouse Genome 430 2.0 Array)   1416310_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028771
Ensembl peptide - ENSMUSP00000068713
NCBI entrez gene - 108907     See in Manteia.
MGI - MGI:2675669
RefSeq - XM_011239246
RefSeq - NM_001042652
RefSeq - NM_133851
RefSeq Peptide - NP_598612
RefSeq Peptide - NP_001036117
swissprot - Q9ERH4
Ensembl - ENSMUSG00000027306
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A1L2F3ENSDARG00000002403Danio rerio
 NUSAP1ENSGALG00000008584Gallus gallus
 NUSAP1ENSG00000137804Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026756  Nucleolar and spindle-associated protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation ISO
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0000281 mitotic cytokinesis ISO
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007076 mitotic chromosome condensation ISO
 biological_processGO:0040001 establishment of mitotic spindle localization ISO
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISO
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008017 microtubule binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0002718 abnormal inner cell mass "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0003988 disorganized embryonic tissue "a lack of the regular arrangement of any embryonic tissues" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:58080]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0004760 increased mitotic index "increased number of cells in G2/M phase" [Bertram_Weiss:Bayer_Schering_Pharma_AG]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0009760 abnormal mitotic spindle "an anomaly in the formation of the ellipsoidal (bipolar) collection of fibers visible during nuclear division and cytokinesis responsible for accurate segregation of chromosomes during mitosis" [ISBN:8185198691 "Rieger R et al Eds Glossary of Genetics Classical and Molecular"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0010380 inner cell mass apoptosis "the cells of the blastocyst that develop into the body of the embryo are undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0011093 complete embryonic lethality at implantation "death of all organisms of a given genotype in a population at the point of implantation (Mus: E4.5)" [MGI:csmith]
Show

Allelic Composition: Ccr2tm1Ifc/Ccr2+,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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