ENSMUSG00000027367


Mus musculus

Features
Gene ID: ENSMUSG00000027367
  
Biological name :Stard7
  
Synonyms : Q8R1R3 / Stard7 / START domain containing 7
  
Possible biological names infered from orthology : Q9NQZ5 / StAR related lipid transfer domain containing 7
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 127270218
Gene end: 127298932
  
Corresponding Affymetrix probe sets: 10475772 (MoGene1.0st)   1445024_at (Mouse Genome 430 2.0 Array)   1449628_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106003
Ensembl peptide - ENSMUSP00000106004
Ensembl peptide - ENSMUSP00000116374
NCBI entrez gene - 99138     See in Manteia.
MGI - MGI:2139090
RefSeq - NM_139308
RefSeq - XM_017319355
RefSeq Peptide - NP_647469
swissprot - F7BBA2
swissprot - Q8BXP7
swissprot - Q8R1R3
Ensembl - ENSMUSG00000027367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stard7ENSDARG00000074858Danio rerio
 Q9NQZ5ENSG00000084090Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pctp / phosphatidylcholine transfer protein isoform 2 / Q9UKL6* / phosphatidylcholine transfer protein*ENSMUSG0000002055314


Protein motifs (from Interpro)
Interpro ID Name
 IPR002913  START domain
 IPR023393  START-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001194 dermatitis "inflammation of the skin" [J:65146]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0001952 increased airway responsiveness "more easily provoked into bronchoconstriction in bronchial provocation tests" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0005596 increased susceptibility to type I hypersensitvity reaction "greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0013648 increased CD11b-high dendritic cell number "increase in the number of dendritic cells expressing high levels of CD11b which usually depend on Irf4 for their development" [MGI:Saran, PMID:23516985]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0014026 abnormal respiratory epithelial transmembrane transport "any anomaly in the directed movement of a substance from one side of the respiratory epithelial cell membrane to the other" [MGI:csmith]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

 MP:0014032 abnormal mucous gland morphology "any structural anomaly of any exocrine gland in which the principal secretory cells are mucus-secreting cells; mucus is a slippery secretion with lubricating or protective function produced by, and covering, mucous membranes; mucous glands typically stain lighter than serous glands during standard histological preparation; most are multicellular, but goblet cells are single-celled glands" [http://en.wikipedia.org/wiki/Mucous_gland, MGI:csmith, UBERON:0000414]
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Allelic Composition: Prf1tm1Sdz/Prf1tm1Sdz,X/Yaa
Genetic Background: BXSB.B6-Prf1tm1Sdz/Dcr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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