ENSMUSG00000027375


Mus musculus

Features
Gene ID: ENSMUSG00000027375
  
Biological name :Mal
  
Synonyms : Mal / Myelin and lymphocyte protein / O09198
  
Possible biological names infered from orthology : mal, T cell differentiation protein / P21145
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 127633226
Gene end: 127656695
  
Corresponding Affymetrix probe sets: 10487441 (MoGene1.0st)   1417275_at (Mouse Genome 430 2.0 Array)   1432558_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028853
Ensembl peptide - ENSMUSP00000028854
NCBI entrez gene - 17153     See in Manteia.
MGI - MGI:892970
RefSeq - NM_001171187
RefSeq - NM_010762
RefSeq Peptide - NP_001164658
RefSeq Peptide - NP_034892
swissprot - O09198
Ensembl - ENSMUSG00000027375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 malENSDARG00000030094Danio rerio
 zgc:153665ENSDARG00000043442Danio rerio
 zgc:158773ENSDARG00000070401Danio rerio
 MALENSGALG00000008552Gallus gallus
 MALENSG00000172005Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mal2 / Q8BI08 / Protein MAL2 / Q969L2* / mal, T cell differentiation protein 2 (gene/pseudogene)*ENSMUSG0000002447941
Mall / Q91X49 / MAL-like protein / Q13021* / mal, T cell differentiation protein like*ENSMUSG0000002737738


Protein motifs (from Interpro)
Interpro ID Name
 IPR008253  Marvel domain
 IPR013295  Myelin and lymphocyte (MAL) protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001766 membrane raft polarization IBA
 biological_processGO:0042552 myelination IEA
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IEA
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0019911 structural constituent of myelin sheath ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Plscr1tm1Lex/Plscr1tm1Lex,Plscr3tm1Sims/Plscr3tm1Sims
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001330 abnormal optic nerve morphology "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plscr1tm1Lex/Plscr1tm1Lex,Plscr3tm1Sims/Plscr3tm1Sims
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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