ENSMUSG00000027457


Mus musculus

Features
Gene ID: ENSMUSG00000027457
  
Biological name :Snph
  
Synonyms : Q80U23 / Snph / Syntaphilin
  
Possible biological names infered from orthology : O15079
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: G3
Gene start: 151590549
Gene end: 151632593
  
Corresponding Affymetrix probe sets: 10488558 (MoGene1.0st)   1435210_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138249
Ensembl peptide - ENSMUSP00000123255
Ensembl peptide - ENSMUSP00000138114
Ensembl peptide - ENSMUSP00000028951
Ensembl peptide - ENSMUSP00000092026
Ensembl peptide - ENSMUSP00000105501
Ensembl peptide - ENSMUSP00000105503
NCBI entrez gene - 241727     See in Manteia.
MGI - MGI:2139270
RefSeq - NM_198214
RefSeq - NM_001291076
RefSeq - NM_001291077
RefSeq - XM_011239535
RefSeq - XM_011239536
RefSeq - XM_011239538
RefSeq - XM_017318256
RefSeq - XM_017318258
RefSeq Peptide - NP_001278005
RefSeq Peptide - NP_001278006
RefSeq Peptide - NP_937857
swissprot - S4R180
swissprot - Q80U23
swissprot - Z4YN82
swissprot - A0A140T8V7
Ensembl - ENSMUSG00000027457
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snphaENSDARG00000078485Danio rerio
 snphbENSDARG00000075539Danio rerio
 SNPHENSGALG00000037274Gallus gallus
 SNPHENSG00000101298Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sybu / Q8BHS8 / syntabulin (syntaxin-interacting) / Q9NX95* / syntabulin*ENSMUSG0000002234039


Protein motifs (from Interpro)
Interpro ID Name
 IPR026196  Syntaphilin
 IPR028197  Syntaphilin/Syntabulin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion ISO
 biological_processGO:0007420 brain development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0045806 negative regulation of endocytosis ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005881 cytoplasmic microtubule ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0017075 syntaxin-1 binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002919 enhanced paired-pulse facilitation "increase in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to greater increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0006036 abnormal mitochondrial physiology 
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008571 abnormal synaptic bouton morphology "any structural anomaly of the knoblike enlargements along the course of axons, or more commonly at the distal terminations of axons which are specialized for the release of neurotransmitters" [MESH:A08.663.542.145.750]
Show

Allelic Composition: Kdm1atm1.2Tche/Kdm1atm1.2Tche
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Prom2tm1.1(KOMP)Vlcg/Prom2+
Genetic Background: C57BL/6N-Prom2tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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