Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000005	increased brown fat amount	"increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208]	Show Allelic Composition: Ar^tm1Chc/Ar^tm1.1Chc,Tmem163^{Tg(ACTB-cre)2Mrt}/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0000024	lowered ear position	"outer ears which are situated below the normal location " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6
MP:0000220	increased monocyte count	"greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0000371	diluted coat color	"a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mertk^tm1Grl/Mertk^tm1Grl,Tyro3^tm1Grl/Tyro3^tm1Grl Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: a/a,Tyr^c-i/Tyr^c-i Genetic Background: involves: STOCK Tyr^c-r Allelic Composition: A/?,Dct^Slt-lt/Dct^Slt-lt Genetic Background: involves: C3H/HeJ Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: A/?,Dct^Slt-lt/Dct⁺ Genetic Background: involves: C3H/HeJ Allelic Composition: A^w/a,Corin^tm1Bamo/Corin^tm1Bamo Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/N Allelic Composition: A^w/A^w,Corin^tm1Bamo/Corin^tm1Bamo Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/N Allelic Composition: A/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a⁺,Oca2^p/Oca2⁺,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: involves: C58 * CT/Ch Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a/a,Hps6^ru-5J/Hps6^ru-5J,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Tyrp1^b/Tyrp1^b,wad/wad⁺ Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b,wad/wad Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified Allelic Composition: A/A,Hps6^ru/Hps6^ru Genetic Background: Not Specified Allelic Composition: a/a,Mreg^dsu/Mreg^dsu,Hps6^ru/Hps6^ru Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: Not Specified Allelic Composition: a/a,Dct^Slt-lt/Dct^Slt-lt Genetic Background: involves: C3H/HeJ Allelic Composition: a/a,Dct^Slt-lt/Dct⁺ Genetic Background: involves: C3H/HeJ Allelic Composition: A/?,Tyr^em1Ove/Tyr^em1Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^c/Tyr^em1Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^em2Ove/Tyr^em2Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^em4Ove/Tyr^em4Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em4Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^c/Tyr^em6Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em7Ove/Tyr^em7Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^c/Tyr^em7Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em8Ove/Tyr^em8Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em9Ove/Tyr^em9Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em9Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em12Ove/Tyr^em12Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^em14Ove/Tyr^em14Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em14Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/a,Tyr^em15Ove/Tyr^em15Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em2Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^c/Tyr^em12Ove Genetic Background: involves: C57BL/6 * FVB
MP:0000372	irregular coat pigmentation	"uneven coloration of the hair" [J:65030]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6 Allelic Composition: A^hvy/A Genetic Background: B6.C3-Bpifa2^a A^hvy Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a^m/a Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iapy/A^iapy Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000417	short hair	"reduced average length of the hairs" [J:64948]	Show Allelic Composition: a^e/a^e,Tbx15^de-H/Tbx15^de-H Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S
MP:0000421	mottled coat	"coat has spots, streaks, and/or blotches of a different color" [J:17194]	Show Allelic Composition: A^vy/A,Dnmt1^MommeD2/Dnmt1⁺ Genetic Background: involves: C57BL/6J * FVB/NJ Allelic Composition: a^m-J/a^m-J Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: a^m-J/a Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iy/A Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^iy/A^iy Genetic Background: C3H/HeJ-A^iy Allelic Composition: a^m/a Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iapy/A^iapy Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000435	shortened head	"reduced anterior-posterior length of the head" [J:42035]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6
MP:0000449	broad nasal bridge	"wider than normal upper part of the ridge of the nose" [J:53370]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6
MP:0000519	hydronephrosis	"dilation of the pelvis and calices of one or both kidneys" [J:56641]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000536	hydroureter	"distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000550	abnormal forelimb morphology	"malformation of the entire anterior extremities" [MGI:tc]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000552	abnormal radius morphology	"malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000554	abnormal carpal bone morphology	"malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000556	abnormal hindlimb morphology	"malformation of the entire posterior extremities" [MGI:tc]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000564	syndactyly	"any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000565	oligodactyly	"congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000566	synostosis	"osseous union of two bones that are not normally connected" [J:13049]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000572	abnormal autopod morphology	"malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0000788	abnormal cerebral cortex morphology	"malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0000823	abnormal lateral ventricle morphology	"malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0000914	exencephaly	"neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0000928	incomplete cephalic closure	"arrest of the fusion of the cephalic neural folds" [J:12622]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0001257	increased body length	"increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Ar^tm1Chc/Ar^tm1.1Chc,Tmem163^{Tg(ACTB-cre)2Mrt}/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
MP:0001260	increased body weight	"greater than normal average weight " [J:33400]	Show Allelic Composition: Ptprj^Scc1-s/? Genetic Background: involves: BALB/cHeA * STS/A Allelic Composition: a/A^y,Zc3h4^KK/Zc3h4^KK Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: a/A^y,Zc3h4^C57BL/6J/Zc3h4^KK Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: a/A^y,Bwq2^KK/Bwq2^KK Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: a/A^y,Bwq10^C57BL/6J/Bwq10^C57BL/6J Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: A^y/A^w Genetic Background: 129S1.C3-A^y/A^w Chr 19^MOLF/Ei
MP:0001261	obese	"excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Npbwr1^tm1Rck/Npbwr1^tm1Rck,Lep^ob/Lep^ob Genetic Background: involves: 129P/Ola * C57BL/6J Allelic Composition: A^vy/a Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^iy/A Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^iy/A^iy Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iapy/A^iapy Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl Allelic Composition: A^y/A,Pepd^dal/Pepd^dal Genetic Background: involves: C3H/HeJ * CBA/J
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Dmbx1^tm1Sse/Dmbx1^tm1Sse,Lep^ob/Lep^ob Genetic Background: involves: ICR Allelic Composition: A^y/a,Agrp^tm2(DTR)Rpa/Agrp⁺ Genetic Background: involves: 129S4/SvJaeSor * KK/Upj Allelic Composition: A^y/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK Allelic Composition: a/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6 Allelic Composition: a^e/a^e,Tbx15^de-H/Tbx15^de-H Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S
MP:0001300	ocular hypertelorism	"increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6
MP:0001324	abnormal eye pigmentation	"change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a/a,Hps6^ru-5J/Hps6^ru-5J,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified Allelic Composition: a/a,Tyr^em2Ove/Tyr^em2Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^em4Ove/Tyr^em4Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em4Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em7Ove/Tyr^em7Ove Genetic Background: involves: C57BL/6 * FVB
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6
MP:0001431	abnormal eating behavior	"inability to consume or atypical consumption pattern" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:19212]	Show Allelic Composition: Agrp^tm2(DTR)Rpa/Agrp⁺,Tg(Pomc-EGFP)1Low/0 Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J Allelic Composition: A^y/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0001433	polyphagia	"eating to excess" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0001510	abnormal coat appearance	"coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mrgprd^tm5Mjz/Mrgprd^tm5Mjz Genetic Background: involves: 129S1/Sv Allelic Composition: a^t-41J/a^t-41J Genetic Background: involves: AKR/J * C57L/J Allelic Composition: a^t-43J/a^t-43J Genetic Background: involves: C3HeB/FeJLe Allelic Composition: A/A,Tyr^c-ch/Tyr^c-ch Genetic Background: Not Specified
MP:0001552	increased circulating triglyceride level	"higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0001559	hyperglycemia	"abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0001759	increased urine glucose level	"a greater level of excretion of glucose in the urine compared to the normal state" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J Allelic Composition: a/A^y,Guq1^KK/Guq1^KK Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: a/A^y,Guq2^C57BL/6J/Guq2^C57BL/6J Genetic Background: involves: C57BL/6J * KK-A^y
MP:0001845	abnormal inflammatory response	"aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [Pathology:ISBN 0-397-51047-0]	Show Allelic Composition: Nkx2-2^tm2.1Suss/Nkx2-2^tm2.1Suss,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,Tg(Ins2-cre)23Herr/0 Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA/J * SJL
MP:0002020	increased tumor incidence	"greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]	Show Allelic Composition: A^vy/a Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0002053	decreased incidence of induced tumors	"reduced frequency of tumor incidence induced by a carcinogen or mutagen" [J:56886]	Show Allelic Composition: A^y/A^w Genetic Background: 129S1.C3-A^y/A^w Chr 19^MOLF/Ei
MP:0002075	abnormal coat color	"irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Jup^tm1Ruiz/Jup^tm1Ruiz Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: A^w-47J/A Genetic Background: C57BL/6J-A^w-47J Allelic Composition: A^w-46J/A^w-46J Genetic Background: C57BL/6J-A^w-46J Allelic Composition: A^w-47J/A^w-47J Genetic Background: C57BL/6J-A^w-47J Allelic Composition: a/a,Tyr^c-i/Tyr^c-i Genetic Background: involves: STOCK Tyr^c-r Allelic Composition: A^vy/A^vy Genetic Background: involves: C3H/HeJ Allelic Composition: a^u/a^u Genetic Background: (C3H/HeH x 101/H)F1 Allelic Composition: a^u/a Genetic Background: (C3H/HeH x 101/H)F1 Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: a^16H/a^l Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^e/a^e Genetic Background: (P x S)F1 Allelic Composition: A/A,Mc1r^E-tob/Mc1r^E-tob Genetic Background: M. m. domesticus poschiavinus Allelic Composition: a^t-2Gso/a^t-2Gso Genetic Background: involves: C57BL/RlGso * SEC/RlGso Allelic Composition: a^9R/a^9R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^1R/a^1R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^2R/a^2R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^3R/a^3R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^4R/a^4R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^5R/a^5R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^6R/a^6R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^7R/a^7R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^8R/a^8R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^10R/a^10R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^11R/a^11R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^12R/a^12R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^13R/a^13R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^14R/a^14R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^15R/a^15R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^16R/a^16R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^17R/a^17R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^18R/a^18R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^19R/a^19R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^20R/a^20R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^21R/a^21R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^22R/a^22R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^23R/a^23R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^24R/a^24R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^25R/a^25R Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^t-42J/? Genetic Background: C57BL/6J-a^t-42J Allelic Composition: A^vy/a Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: a^t/a^t Genetic Background: Not Specified Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru Allelic Composition: a^td/a Genetic Background: C57BL/6J-a^td/J Allelic Composition: a^td/a^td Genetic Background: C57BL/6J-a^td/J Allelic Composition: A^iy/A Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^iy/A^iy Genetic Background: C3H/HeJ-A^iy Allelic Composition: a/a,U/U Genetic Background: Not Specified Allelic Composition: A/A,U/U Genetic Background: Not Specified Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: a^16H/a^e Genetic Background: involves: 101/H * C3H/HeH * P * S Allelic Composition: a^twp/a^twp Genetic Background: involves: AB/Hum-1 Allelic Composition: a/a^twp Genetic Background: Not Specified Allelic Composition: A/a^twp Genetic Background: Not Specified Allelic Composition: As/As,A/A Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^t/A,As/As⁺ Genetic Background: Not Specified Allelic Composition: A^w/A^w,As/As Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^t/a^t,As/As Genetic Background: Not Specified Allelic Composition: A^w/a^t,As/As⁺ Genetic Background: Not Specified Allelic Composition: A^hvy/A Genetic Background: B6.C3-Bpifa2^a A^hvy Allelic Composition: A^hvy/A^hvy Genetic Background: B6.C3-Bpifa2^a A^hvy Allelic Composition: a/a,Hps6^ru-5J/Hps6^ru-5J,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a^t-44J/? Genetic Background: B6.C/(HZ18)By Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iapy/A^iapy Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: a^x/a Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^x/a Genetic Background: B6.Cg-a^x Allelic Composition: a^x/a^e Genetic Background: B6.Cg-a^x Allelic Composition: a/a^13H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^13H/a^13H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^17H/a^17H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a/a^17H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^19H/a^19H Genetic Background: involves: C3H/HeH Allelic Composition: a/a^19H Genetic Background: involves: C3H/HeH Allelic Composition: a/a^20H Genetic Background: Not Specified Allelic Composition: a^20H/a^20H Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified Allelic Composition: A^w-15J/a Genetic Background: involves: C57BL/6J * DBA/2J Allelic Composition: a/A^w-20J Genetic Background: involves: C57BL/6J Allelic Composition: a/A^w-22J Genetic Background: C57BL/10Rk Allelic Composition: A/A,Tyr^c-ch/Tyr^c-ch Genetic Background: Not Specified Allelic Composition: a/a Genetic Background: Not Specified Allelic Composition: A^w-26J/a Genetic Background: C57BL/6J-A^w-26J/a Allelic Composition: A^w-27J/a Genetic Background: C57BL/6J-A^w-27J Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: Not Specified Allelic Composition: A/a^tl Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^tl/a^tl Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^t/a^tl Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: A/A,Mc1r^E-tob/Mc1r⁺ Genetic Background: M. m. domesticus poschiavinus
MP:0002079	increased circulating insulin level	"greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0002080	prenatal lethality	"death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Avpr2^tm1Jwe/Avpr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CF-1 Allelic Composition: a^jl41/a^jl41 Genetic Background: Not Specified Allelic Composition: a^jl85/a^jl85 Genetic Background: Not Specified Allelic Composition: a^l/a^l Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^16H/a^16H Genetic Background: involves: 101/H * C3H/HeH
MP:0002095	abnormal skin pigmentation	"variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Jup^tm1Ruiz/Jup^tm1Ruiz Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: A^w-47J/A Genetic Background: C57BL/6J-A^w-47J Allelic Composition: A^w-46J/A^w-46J Genetic Background: C57BL/6J-A^w-46J Allelic Composition: A^w-47J/A^w-47J Genetic Background: C57BL/6J-A^w-47J Allelic Composition: a^e/a^e,Tbx15^de-H/Tbx15^de-H Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S
MP:0002118	abnormal lipid homeostasis	"anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0002135	abnormal kidney morphology	"abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Nkx2-2^tm2.1Suss/Nkx2-2^tm2.1Suss,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,Tg(Ins2-cre)23Herr/0 Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA/J * SJL
MP:0002136	abnormal kidney physiology	"altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0002544	brachydactyly	"abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0002703	abnormal renal tubules	"anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0002705	dilated renal tubules	"enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0002877	abnormal melanocyte morphology	"malformation of the cells that produce pigment " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified
MP:0002938	white spotting	"the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Kit^W-2J/Kit⁺ Genetic Background: involves: C57BL/6J
MP:0002940	variable body spotting	"the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: A^y/a,Ednrb^s/Ednrb^s Genetic Background: Not Specified
MP:0002981	increased liver weight	"a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6
MP:0003121	genomic imprinting	"phenotype resulting from inactivation of specific loci during gametogenesis, but not encoded by the DNA itself" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Dkc1^tm1.1Bsl/Dkc1⁺,Tg(Gata1-cre)1Sho/0 Genetic Background: involves: 129/Sv * C57BL/6 * CD-1
MP:0003122	maternal imprinting	"specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: a^m-J/a^m-J Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0003136	yellow coat color	"amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]	Show Allelic Composition: Cblb^tm1Hua/Cblb^tm1Hua Genetic Background: Not Specified Allelic Composition: A^sy/a Genetic Background: C57BL/6J-A^sy/a/J Allelic Composition: A^vy/A,Smchd1^MommeD1/Smchd1⁺ Genetic Background: involves: C57BL/6J * FVB/NJ Allelic Composition: A^vy/A,Dnmt1^MommeD2/Dnmt1⁺ Genetic Background: involves: C57BL/6J * FVB/NJ Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6 Allelic Composition: A^w/? Genetic Background: Not Specified Allelic Composition: A^y/a,Tyrp1^B-lt/? Genetic Background: Not Specified Allelic Composition: A^y-Jkn/A Genetic Background: involves: C57BL/6N Allelic Composition: A^y-Jkn/A,Mc1r^e/Mc1r^e Genetic Background: involves: C57BL/6Ha * C57BL/6N Allelic Composition: A^y-Jkn/A,Mc1r^e/Mc1r^e,Tg(MC1R)1Jkn/0 Genetic Background: involves: C57BL/6Ha * C57BL/6N Allelic Composition: a/A,Pomc^tm1Sora/Pomc^tm1Sora Genetic Background: involves: 129S6/SvEvTac Allelic Composition: a/A,Mc1r^e/Mc1r^e,Pomc^tm1Sora/Pomc^tm1Sora,Tg(MC1R)1Jkn/? Genetic Background: involves: 129S6/SvEvTac * C57BL/6Ha Allelic Composition: a/a,Mc1r^e/Mc1r^e,Pomc^tm1Sora/Pomc^tm1Sora,Tg(MC1R)1Jkn/? Genetic Background: involves: 129S6/SvEvTac * C57BL/6Ha Allelic Composition: A^iy/A Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^iy/A^iy Genetic Background: C3H/HeJ-A^iy Allelic Composition: A^hvy/A Genetic Background: B6.C3-Bpifa2^a A^hvy Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^iapy/A^iapy Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^y/A Genetic Background: involves: C3H/HeJ * C57BL/6J-A^y/a Allelic Composition: A^y-J/? Genetic Background: C3HeB/FeJ-A^y-J
MP:0003171	phenotypic reversion	"reverse mutation to wild-type phenotype from a previously characterized mutant phenotype" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Mreg^dsu/Mreg^dsu,Hps6^ru/Hps6^ru Genetic Background: involves: C57BL/6J Allelic Composition: A^tm1.1Arte/a Genetic Background: C57BL/6NTac-A^tm1.1Arte/a
MP:0003402	decreased liver weight	"reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: A^y/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK Allelic Composition: a/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0003446	renal hypoplasia	"decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0003451	absent olfactory bulb	"absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0003586	ureter dilation	"abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0003604	single kidney		Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0003718	maternal effect	"expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a^m/a Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: A^iapy/? Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: A^y/A^y Genetic Background: 101-A^y
MP:0003809	abnormal hair shaft morphology	"irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a^t-43J/a^t-43J Genetic Background: involves: C3HeB/FeJLe
MP:0004165	abnormal lateral geniculate nucleus morphology	"any malformation or absence of the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0004356	radius hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, in the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0004381	abnormal hair follicle melanocyte morphology	"any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: Not Specified
MP:0004382	abnormal hair follicle melanogenesis	"failure of or anomaly in the biosynthetic pathway of melanin formation in hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Thap11^tm1.1Tpz/Thap11^tm1.1Tpz Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: A^w-J/A^w-J Genetic Background: C57BL/6J-A^w-J/J
MP:0004725	decreased platelet serotonin level	"reduced concentration of serotonin in the platelets; this biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru Allelic Composition: a/a,Rab27a^ash/Rab27a^ash Genetic Background: involves: C3H/HeSnJ * C57BL/6J
MP:0004893	decreased adiponectin level	"reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc,Ccr2^tm1Mae/Ccr2^tm1Mae Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0005071	enlarged melanin granules in hair follicle	"increased size of the pigment particles in the hair follicle" [J:5078]	Show Allelic Composition: Gria4^tm1Dgen/Gria4^tm1Dgen Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0005072	abnormal hair follicle melanin granule	"anomalous pigment paricles in the hair follicles" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Gria4^tm1Dgen/Gria4^tm1Dgen Genetic Background: involves: 129P2/OlaHsd * C57BL/6J Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified
MP:0005075	abnormal melanosome morphology	"anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]	Show Allelic Composition: Sox11^tm1Weg/Sox11^tm1Weg Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyr^c/Tyr^c Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Oca2^p-J/Oca2^p-J Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J Allelic Composition: a/a,Hps6^ru/Hps6^ru,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J
MP:0005077	abnormal melanogenesis	"failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]	Show Allelic Composition: Lfng^tm1Rjo/Lfng^tm1Rjo,Mesp2^{tm15.1(Lfng)Ysa}/Mesp2⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: a/a,Oca2^p-J/Oca2^p-J Genetic Background: involves: C3H/HeJ Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyr^c/Tyr^c Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Hps6^ru/Hps6^ru,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J
MP:0005100	abnormal choroid pigmentation	"anomalous coloring of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified
MP:0005102	abnormal iris pigmentation	"anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified
MP:0005104	abnormal tarsus morphology	"malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0005108	abnormal ulna morphology	"malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0005118	decreased circulating pituitary hormone level	"less than expected concentration of any of the pituitary hormones found in the blood" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Igh-J^tm1Jkbv/Igh-J^tm1Jkbv,Igkc^tm1Jkbv/Igkc^tm1Jkbv,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0005171	lack of coat pigmentation	"fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]	Show Allelic Composition: a^t/a^t Genetic Background: Not Specified Allelic Composition: A^w-35J/? Genetic Background: involves: C57BL Allelic Composition: A^w-36J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-37J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-38J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-39J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-40J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-41J/? Genetic Background: involves: C57BL Allelic Composition: A^w-42J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^w-43J/? Genetic Background: involves: C57BL/6J Allelic Composition: A^tm1.1Arte/A^tm1.1Arte,Tyr^tm1Arte/Tyr^tm1Arte Genetic Background: C57BL/6NTac-A^tm1.1Arte Tyr^tm1Arte
MP:0005172	lack of eye pigmentation	"visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]	Show Allelic Composition: Mertk^tm1Grl/Mertk^tm1Grl,Tyro3^tm1Grl/Tyro3^tm1Grl Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified Allelic Composition: a/a,Hps6^ru-5J/Hps6^ru-5J,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: A/?,Tyr^c/Tyr^em1Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em9Ove/Tyr^em9Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em12Ove/Tyr^em12Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: a/a,Tyr^c/Tyr^em2Ove Genetic Background: involves: C57BL/6 * FVB
MP:0005174	abnormal tail pigmentation	"anomalous color of the tail in relation to control animals" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Sdcbp^{tm1c(KOMP)Wtsi}/Sdcbp⁺,Tsc2^tm1Tno/Tsc2⁺,Tg(Camk2a-cre)2Gsc/0 Genetic Background: involves: 129S4/SvJae * C57BL/6N * FVB/N Allelic Composition: a/a,In(11Trp53;11Wnt3)8Brd/+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6Brd * C57BL/6J Allelic Composition: a/a,Tyr^em2Ove/Tyr^em2Ove Genetic Background: involves: C57BL/6 * FVB
MP:0005178	increased total circulating cholesterol level	"greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc,Ccr2^tm1Mae/Ccr2^tm1Mae Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0005215	abnormal islet of Langerhans morphology	"anomalous morphology of these structures that are scattered throughout the pancreas and comprise its endocrine portion; within each islet there are three cell types: alpha, beta, and delta " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0005264	glomerulosclerosis	"hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0005287	narrow eye opening	"less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6
MP:0005292	improved glucose tolerance	"better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: A^y/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK Allelic Composition: a/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0005293	impaired glucose tolerance	"less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0005325	abnormal glomerulus	"anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J
MP:0005331	insulin resistance	"diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Qdpr^tm1Jcs/Qdpr⁺,Tapt1^L5Jcs1/Tapt1⁺ Genetic Background: involves: 101/H * 129S4/SvJae * C3H/HeH * C3HeB/FeJ * C57BL/6J Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0005338	atherosclerotic lesions	"thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0005341	decreased susceptibility to atherosclerosis	"less likely than the norm to develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0005353	abnormal patella morphology	"anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0005366	variegated coat color	"dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: A^vy/a Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: A^vy/a Genetic Background: involves: C57BL/6J
MP:0005408	hypopigmentation	"dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: Not Specified
MP:0005409	darkened coat color	"amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreasesd when compared to wild-type agouti" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Sox18^Mhdadcc1/Sox18⁺ Genetic Background: C3HeB/FeJ-Sox18^Mhdadcc1/Ieg Allelic Composition: a^jl10/a Genetic Background: Not Specified Allelic Composition: a^jl41/a Genetic Background: Not Specified Allelic Composition: a^jl85/a Genetic Background: Not Specified Allelic Composition: a^6H/a^6H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a/a^6H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^e/a^e Genetic Background: (P x S)F1 Allelic Composition: A/A,Mc1r^E-tob/Mc1r^E-tob Genetic Background: M. m. domesticus poschiavinus Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl Allelic Composition: a/a,U/U Genetic Background: Not Specified Allelic Composition: A/A,U/U Genetic Background: Not Specified Allelic Composition: As/As,A/A Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: A^w/A^w,As/As Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^t/a^t,As/As Genetic Background: Not Specified Allelic Composition: A^hvy/A Genetic Background: B6.C3-Bpifa2^a A^hvy Allelic Composition: a^da/a^da Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^5mnu/a^5mnu Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a/a Genetic Background: Not Specified Allelic Composition: a^tl/a^tl Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: A^y/A,Pepd^dal/Pepd^dal Genetic Background: involves: C3H/HeJ * CBA/J Allelic Composition: A^y/a,Sik2^tm1Htake/Sik2⁺ Genetic Background: C57BL/6-Sik2^tm1Htake Allelic Composition: A/A,Mc1r^E-tob/Mc1r⁺ Genetic Background: M. m. domesticus poschiavinus
MP:0005430	absent fibula	"missing the lateral and shorter of the two bones of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86196]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0005449	abnormal food intake	"anomalous total number of calories taken in daily when compared to the norm" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Thap11^tm1.1Tpz/Thap11^tm1.1Tpz Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005455	increased weight gain	"greater increase in body weight over existing weight when compared to the average increase in weight on the same diet, with equal energy (calorie) intake " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:42702]	Show Allelic Composition: a/A^y,Bwq2^KK/Bwq2^KK Genetic Background: involves: C57BL/6J * KK-A^y Allelic Composition: A^y/a Genetic Background: involves: KK Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b⁺ Genetic Background: involves: C57BL/6
MP:0005458	increased percent body fat	"more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b⁺ Genetic Background: involves: C57BL/6
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: a^e/a^e,Tbx15^de-H/Tbx15^de-H Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: A^y/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK Allelic Composition: a/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0005606	increased bleeding time	"greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru Allelic Composition: a/a,Rab27a^ash/Rab27a^ash Genetic Background: involves: C3H/HeSnJ * C57BL/6J
MP:0005669	increased circulating leptin level	"greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc,Ccr2^tm1Mae/Ccr2^tm1Mae Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0006370	abnormal phaeomelanin content	"anomaly in the amount or distribution of yellow pigment in the hair" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/A,Pomc^tm1Sora/Pomc^tm1Sora Genetic Background: involves: 129S6/SvEvTac Allelic Composition: a/A,Mc1r^e/Mc1r^e,Pomc^tm1Sora/Pomc^tm1Sora,Tg(MC1R)1Jkn/? Genetic Background: involves: 129S6/SvEvTac * C57BL/6Ha Allelic Composition: a/a,Mc1r^e/Mc1r^e,Pomc^tm1Sora/Pomc^tm1Sora,Tg(MC1R)1Jkn/? Genetic Background: involves: 129S6/SvEvTac * C57BL/6Ha Allelic Composition: A/A,Tyr^c-ch/Tyr^c-ch Genetic Background: Not Specified
MP:0008056	abnormal retinal ganglion cell morphology	"any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0008237	abnormal ventral coat pigmentation	"irregular or unusual pigmentation of ventrum hair in relation to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6 Allelic Composition: a^t-42J/? Genetic Background: C57BL/6J-a^t-42J Allelic Composition: A^w/? Genetic Background: Not Specified Allelic Composition: A^w-J/A^w-J Genetic Background: C57BL/6J-A^w-J/J Allelic Composition: a^td/a Genetic Background: C57BL/6J-a^td/J Allelic Composition: a^td/a^td Genetic Background: C57BL/6J-a^td/J Allelic Composition: a^twp/a^twp Genetic Background: involves: AB/Hum-1 Allelic Composition: a/a^twp Genetic Background: Not Specified Allelic Composition: A/a^twp Genetic Background: Not Specified Allelic Composition: a^t-44J/? Genetic Background: B6.C/(HZ18)By Allelic Composition: a^t-41J/a^t-41J Genetic Background: involves: AKR/J * C57L/J Allelic Composition: a^t-43J/a^t-43J Genetic Background: involves: C3HeB/FeJLe Allelic Composition: a^x/a Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: a^x/a Genetic Background: B6.Cg-a^x Allelic Composition: a^x/a^e Genetic Background: B6.Cg-a^x Allelic Composition: A^w-15J/a Genetic Background: involves: C57BL/6J * DBA/2J Allelic Composition: a/A^w-20J Genetic Background: involves: C57BL/6J Allelic Composition: a/A^w-22J Genetic Background: C57BL/10Rk Allelic Composition: A^w-26J/a Genetic Background: C57BL/6J-A^w-26J/a Allelic Composition: A^w-27J/a Genetic Background: C57BL/6J-A^w-27J
MP:0008238	abnormal dorsoventral coat patterning	"irregular or unusual pigmentation pattern of the dorsal-to-ventral axis compared to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Nkx3-1^tm1Saa/Nkx3-1^tm1Saa,Tg(KLK3-cre)13Saa/? Genetic Background: involves: C57BL/6 Allelic Composition: a^t/a^t Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified Allelic Composition: A/A,Dkd/Dkd Genetic Background: LPT;C3-Dkd/GrsrJ Allelic Composition: a^td/a Genetic Background: C57BL/6J-a^td/J Allelic Composition: a^td/a^td Genetic Background: C57BL/6J-a^td/J Allelic Composition: a^t-33J/a^t-33J Genetic Background: C57BL/6J-a^t-33J/J Allelic Composition: a^da/a^da Genetic Background: involves: 101/H * C3H/HeH
MP:0008296	abnormal x-zone morphology	"any structural anomaly of the transient cortical layer juxtaposed to the medulla and the zona reticularis; in males, this zone rapidly involutes at the onset of puberty whereas this zone persists in females until the first pregnancy or later in adulthood in non-pregnant females" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:3582592]	Show Allelic Composition: Apoe^tm1Unc/Apoe^tm1Unc,Npc1^m1N/Npc1^m1N Genetic Background: involves: 129P2/OlaHsd * BALB/c
MP:0008480	absent eye pigmentation	"absence of melanin (pigment) in the eye either due to absent melanocytes or failure of melanin synthesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: A^tm1.1Arte/A^tm1.1Arte,Tyr^tm1Arte/Tyr^tm1Arte Genetic Background: C57BL/6NTac-A^tm1.1Arte Tyr^tm1Arte
MP:0008731	abnormal hair shaft melanin granules	"any amount or distribution anomaly of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0008732	reduced hair shaft melanin granule number	"the number of pigment polymers in the hair shaft is less than normal" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0008733	abnormal hair shaft melanin granule distribution	"disruption in the regular arrangement of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: Not Specified Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: Not Specified
MP:0008762	embryonic lethality	"death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: a^x/a Genetic Background: B6.Cg-a^x Allelic Composition: A^y/A^y Genetic Background: 101-A^y
MP:0008915	fused carpal bones	"anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0008919	fused tarsal bones	"anomaly of the eight bones of the instep of the paw/foot resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: a^{jIs(17;In2)1Gso}/a^{jIs(17;In2)1Gso},Fmn1^{ld-Is(17;In2)1Gso}/Fmn1^{ld-Is(17;In2)1Gso} Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/E * SEC/Rl
MP:0008934	absent choroid plexus	"absence of the fringe of the tela choroidea of the brain ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: a/a,Pax3^Sp-1H/Pax3^Sp-1H Genetic Background: involves: 101/H * C3H/HeH * C57BL/6
MP:0009255	degranulated pancreatic beta cells	"insulin-secreting cells of the pancreas do not contain vesicles containing insulin" [MGI:acv "Alicia Valenzuela, Genetic Resources Curator"]	Show Allelic Composition: A^y/a Genetic Background: involves: KK
MP:0009283	decreased gonadal fat pad weight	"less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Rmi1^{Gt(pUHachi)0283Imeg}/Rmi1⁺ Genetic Background: involves: C57BL/6 * KK
MP:0009285	increased gonadal fat pad weight	"greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0009292	increased inguinal fat pad weight		Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0009304	increased retroperitoneal fat pad weight		Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6 Allelic Composition: A^y/A,Prkar2b^tm2Gsm/Prkar2b^tm2Gsm Genetic Background: involves: C57BL/6
MP:0009448	decreased platelet ATP level	"reduced concentration of the major energy source adenosine triphosphate produced by dense bodies located in platelets" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0009554	abnormal hair follicle melanin granule shape	"the form of pigment polymers in the hair follicle differs compared to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified
MP:0009555	abnormal hair follicle melanin granule distribution	"anomaly in the spatial arrangement of particles produced by melanocytes that confer color in the hair follicle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: involves: DBA/2J Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: involves: C57BL/J * C57BR
MP:0009557	decreased platelet ADP level	"reduced concentration of the major energy source adenosine diphosphate produced by dense bodies located in platelets" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0009928	abnormal pinna hair pigmentation	"amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreased or increased in hair located behind the ears when compared to control animal pigmentation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a^6H/a^6H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a/a^6H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^da/a^da Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^13H/a^13H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^17H/a^17H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a^19H/a^19H Genetic Background: involves: C3H/HeH Allelic Composition: a^20H/a^20H Genetic Background: Not Specified
MP:0009933	abnormal tail hair pigmentation	"an anomaly in the expected coloration of hair on the dorsal and/or ventral surface of the tail" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a^20H/a^20H Genetic Background: Not Specified
MP:0010024	increased total body fat amount	"greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: A^y/a Genetic Background: involves: KK
MP:0010192	abnormal retinal melanin granule morphology	"any structural anomaly of the pigment particles in the retina" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]	Show Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: involves: C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyr^c/Tyr^c Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Hps6^ru/Hps6^ru,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyrp1^b/Tyrp1^b Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Bloc1s6^pa/Bloc1s6^pa Genetic Background: involves: C57BL/6J
MP:0010193	abnormal choroid melanin granule morphology	"any structural anomaly of the pigment particles in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]	Show Allelic Composition: a/a,Oca2^p-J/Oca2^p-J Genetic Background: involves: C3H/HeJ Allelic Composition: a/a,Lyst^bg/Lyst^bg Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyr^c/Tyr^c Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Oca2^p-J/Oca2^p-J Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyrp1^b/Tyrp1^b Genetic Background: involves: C3H/Rl * C57BL/6J Allelic Composition: a/a,Myo5a^d/Myo5a^d Genetic Background: involves: DBA/2J Allelic Composition: a/a,Mlph^ln/Mlph^ln Genetic Background: involves: C57BL/J * C57BR
MP:0011093	complete embryonic lethality at implantation	"death of all organisms of a given genotype in a population at the point of implantation (Mus: E4.5)" [MGI:csmith]	Show Allelic Composition: A^y/A^y Genetic Background: 101-A^y
MP:0011095	complete embryonic lethality between implantation and placentation	"death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]	Show Allelic Composition: a^t-43J/a^t-43J Genetic Background: involves: C3HeB/FeJLe
MP:0011277	decreased tail pigmentation	"visually detectable dilution of pigment present on the tail surface" [MGI:csmith]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a/a,Tyr^em4Ove/Tyr^em4Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em8Ove/Tyr^em8Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/a,Tyr^em15Ove/Tyr^em15Ove Genetic Background: involves: C57BL/6 * FVB
MP:0011279	decreased ear pigmentation	"visually detectable dilution of pigment present in the outer ear" [MGI:csmith]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: A/a,In(11Trp53;11Wnt3)8Brd/+ Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6Brd) or (involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6Brd) or (involves: 129S5/SvEvBrd * C57BL/6Brd * C57BL/6J) Allelic Composition: A/?,Tyr^em8Ove/Tyr^em8Ove Genetic Background: involves: C57BL/6 * FVB
MP:0011339	abnormal glomerular mesangium morphology	"any structural anomaly of the inner layer of the glomerulus within the basement membrane surrounding the glomerular capillaries that contain the intraglomerular mesangial cells" [MGI:csmith]	Show Allelic Composition: A^y/a,Apoe^tm1Unc/Apoe^tm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl
MP:0011353	expanded mesangial matrix	"increase in the amount of mesangial matrix present in the basement membrane surrounding the glomerular capillaries that also contain the intraglomerular mesangial cells" [MGI:csmith]	Show Allelic Composition: A^y/a Genetic Background: involves: KK
MP:0011402	renal cast	"any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna]	Show Allelic Composition: A^y/a Genetic Background: involves: KK
MP:0011409	increased renal glomerulus basement membrane thickness	"increased width of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule" [MGI:anna]	Show Allelic Composition: A^y/a Genetic Background: involves: KK
MP:0011551	variegated eye pigmentation pattern	"an irregular and random patchwork of two or more colors in the eye" [MGI:llw2]	Show Allelic Composition: A/?,Tyr^c/Tyr^em6Ove Genetic Background: involves: C57BL/6 * FVB Allelic Composition: A/?,Tyr^em8Ove/Tyr^em8Ove Genetic Background: involves: C57BL/6 * FVB
MP:0011627	decreased skin pigmentation	"visually detectable dilution of pigment present in the skin" [MGI:csmith]	Show Allelic Composition: a/a,Oca2^p/Oca2^p Genetic Background: Not Specified
MP:0011939	increased food intake	"increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]	Show Allelic Composition: A^y/A Genetic Background: involves: C57BL/6
MP:0012167	abnormal epigenetic regulation of gene expression	"any anomaly in the process that modulates the frequency, rate or extent of gene expression, in which the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence" [GO:0040029]	Show Allelic Composition: A^vy/a Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: A^vy/a Genetic Background: involves: C57BL/6J
MP:0020432	decreased platelet dense granule number	"decreased number of the electron-dense bodies occurring in blood platelets that store and secrete adenosine nucleotides and serotonin" [orcid.org/0000-0003-4606-0597]	Show Allelic Composition: a/a,Hps6^ru/Hps6^ru Genetic Background: B6.Cg-Hps6^ru
MP:0030050	large mandible	"increased size of the lower bony framework of the mouth where the inferior teeth are held" [MGI:anna]	Show Allelic Composition: Ets1^tm1Fwa/Ets1^tm1Fwa Genetic Background: B6.129S4-Ets1^tm1Fwa Allelic Composition: a/a,Mssq1^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq2^C57BL/6JJcl/Mssq2^KK/TaJcl Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq3^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq3^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq4^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq4^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq5^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq5^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq6^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq6^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq6^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq6^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq7^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq7^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq8^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq9^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq9^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq10^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq10^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq11^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq11^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq12^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq12^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq13^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq13^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq13^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq13^C57BL/6JJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq14^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq14^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq15^C57BL/6JJcl/Mssq15^KK/TaJcl Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: a/a,Mssq16^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl Allelic Composition: A^y/a,Mssq16^KK/TaJcl/? Genetic Background: involves: C57BL/6JJcl * KK/TaJcl

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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