ENSMUSG00000027601


Mus musculus

Features
Gene ID: ENSMUSG00000027601
  
Biological name :Mtfr1
  
Synonyms : mitochondrial fission regulator 1 / Mtfr1 / Q99MB2
  
Possible biological names infered from orthology : Q15390
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: A2
Gene start: 19187327
Gene end: 19220817
  
Corresponding Affymetrix probe sets: 10490955 (MoGene1.0st)   1424946_a_at (Mouse Genome 430 2.0 Array)   1451536_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115983
Ensembl peptide - ENSMUSP00000117132
Ensembl peptide - ENSMUSP00000123464
Ensembl peptide - ENSMUSP00000119724
Ensembl peptide - ENSMUSP00000029129
Ensembl peptide - ENSMUSP00000112752
Ensembl peptide - ENSMUSP00000112824
NCBI entrez gene - 67472     See in Manteia.
MGI - MGI:1914722
RefSeq - NM_001253391
RefSeq - XM_011249708
RefSeq - XM_006535526
RefSeq - NM_026182
RefSeq - NM_001253390
RefSeq Peptide - NP_001240319
RefSeq Peptide - NP_001240320
RefSeq Peptide - NP_001343224
RefSeq Peptide - NP_080458
swissprot - F8WI92
swissprot - D3Z5W5
swissprot - Q3TTQ5
swissprot - D3YZ89
swissprot - D6RFQ6
swissprot - Q99MB2
Ensembl - ENSMUSG00000027601
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtfr1ENSDARG00000045304Danio rerio
 MTFR1ENSGALG00000038385Gallus gallus
 MTFR1ENSG00000066855Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mtfr2 / Q8VED8 / Mitochondrial fission regulator 2 / Q6P444*ENSMUSG0000001999228
Mtfr1l / Q9CWE0 / Mus musculus mitochondrial fission regulator 1-like (Mtfr1l), transcript variant 3, mRNA. / Q9H019* / mitochondrial fission regulator 1 like*ENSMUSG0000004667122


Protein motifs (from Interpro)
Interpro ID Name
 IPR007972  Mitochondrial fission regulator 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IBA
 biological_processGO:0007005 mitochondrion organization ISS
 biological_processGO:0009060 aerobic respiration IMP
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008412 increased cellular sensitivity to oxidative stress "greater incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Jarid2Gt(pGT1.8geo)6Pgr/Jarid2Gt(pGT1.8geo)6Pgr
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rgs2tm1.1Kjb/Rgs2tm1.1Kjb,Tg(Tek-cre/ERT2)1Arnd/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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