ENSMUSG00000027649


Mus musculus

Features
Gene ID: ENSMUSG00000027649
  
Biological name :Ctnnbl1
  
Synonyms : Beta-catenin-like protein 1 / Ctnnbl1 / Q9CWL8
  
Possible biological names infered from orthology : catenin beta like 1 / Q8WYA6
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 157737401
Gene end: 157891614
  
Corresponding Affymetrix probe sets: 10477994 (MoGene1.0st)   1448582_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029178
NCBI entrez gene - 66642     See in Manteia.
MGI - MGI:1913892
RefSeq - NM_025680
RefSeq - XM_006500022
RefSeq Peptide - NP_079956
swissprot - Q9CWL8
Ensembl - ENSMUSG00000027649
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctnnbl1ENSDARG00000011958Danio rerio
 CTNNBL1ENSGALG00000006817Gallus gallus
 Q8WYA6ENSG00000132792Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR013180  Beta-catenin-like protein 1, N-terminal
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0016445 somatic diversification of immunoglobulins IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 cellular_componentGO:0000974 Prp19 complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004816 abnormal class switch recombination "anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL

 MP:0005093 impaired B cell proliferation "absent or reduced ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL

Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0005153 abnormal B cell proliferation "change from the norm in the ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Camk2atm1.1Yelg/Camk2atm1.1Yelg,Emx1tm1.1(cre)Ito/0
Genetic Background: B6J.Cg-Camk2atm1.1Yelg Emx1tm1.1(cre)Ito

Allelic Composition: Ctnnbl1tm1.2Crad/Ctnnbl1tm1.2Crad
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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