ENSMUSG00000027674


Mus musculus

Features
Gene ID: ENSMUSG00000027674
  
Biological name :Pex5l
  
Synonyms : Pex5l / PEX5-related protein / Q8C437
  
Possible biological names infered from orthology : peroxisomal biogenesis factor 5 like / Q8IYB4
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A3
Gene start: 32949408
Gene end: 33143247
  
Corresponding Affymetrix probe sets: 10497713 (MoGene1.0st)   1438399_at (Mouse Genome 430 2.0 Array)   1446144_at (Mouse Genome 430 2.0 Array)   1451062_a_at (Mouse Genome 430 2.0 Array)   1458932_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142196
Ensembl peptide - ENSMUSP00000141454
Ensembl peptide - ENSMUSP00000142008
Ensembl peptide - ENSMUSP00000077353
Ensembl peptide - ENSMUSP00000103856
Ensembl peptide - ENSMUSP00000103859
Ensembl peptide - ENSMUSP00000103860
Ensembl peptide - ENSMUSP00000103861
Ensembl peptide - ENSMUSP00000141387
NCBI entrez gene - 58869     See in Manteia.
MGI - MGI:1916672
RefSeq - XM_011249703
RefSeq - XM_011249692
RefSeq - XM_011249693
RefSeq - XM_011249694
RefSeq - XM_011249695
RefSeq - XM_011249696
RefSeq - XM_011249697
RefSeq - XM_011249698
RefSeq - XM_011249699
RefSeq - XM_011249700
RefSeq - XM_011249701
RefSeq - XM_011249702
RefSeq - NM_001163516
RefSeq - NM_001163517
RefSeq - NM_001289505
RefSeq - NM_001310460
RefSeq - NM_021483
RefSeq - XM_006535506
RefSeq - XM_006535507
RefSeq - XM_006535508
RefSeq - XM_011249688
RefSeq - XM_011249689
RefSeq - XM_011249690
RefSeq - XM_011249691
RefSeq Peptide - NP_001156989
RefSeq Peptide - NP_001276434
RefSeq Peptide - NP_001297389
RefSeq Peptide - NP_067458
RefSeq Peptide - NP_001156988
swissprot - D3YYH0
swissprot - F8SLQ1
swissprot - F8SLQ3
swissprot - F8SLQ6
swissprot - F8SLP9
swissprot - Q8C437
Ensembl - ENSMUSG00000027674
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pex5laENSDARG00000022518Danio rerio
 pex5lbENSDARG00000074403Danio rerio
 PEX5LENSGALG00000043386Gallus gallus
 PEX5LENSG00000114757Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pex5 / O09012 / Peroxisomal targeting signal 1 receptor / P50542* / peroxisomal biogenesis factor 5*ENSMUSG0000000506936


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023392  Mitochondrial outer membrane translocase complex, Tom20 domain superfamily
 IPR024111  Peroxisomal targeting signal 1 receptor family
 IPR024112  PEX5-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016560 protein import into peroxisome matrix, docking IBA
 biological_processGO:0042391 regulation of membrane potential IGI
 biological_processGO:0043949 regulation of cAMP-mediated signaling ISS
 biological_processGO:0045185 maintenance of protein location IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005778 peroxisomal membrane IBA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0000268 peroxisome targeting sequence binding ISO
 molecular_functionGO:0005052 peroxisome matrix targeting signal-1 binding ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031267 small GTPase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001447 abnormal nest building behavior "deviation from the usual behavior of mice to build sleeping nests out of any available materials; also of female mice to bulid nests to protect offspring" [J:42758, What s wrong with my mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Prkcdtm1Qxu/Prkcdtm1Qxu
Genetic Background: B6.129P2-Prkcdtm1Qxu

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Prkcdtm1Qxu/Prkcdtm1Qxu
Genetic Background: B6.129P2-Prkcdtm1Qxu

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itgb1tm1Efu/Itgb1tm1Efu,Tg(NPHS2-cre)295Lbh/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

 MP:0002804 abnormal motor learning "defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Prkcdtm1Qxu/Prkcdtm1Qxu
Genetic Background: B6.129P2-Prkcdtm1Qxu

 MP:0003360 depression-related behavior 
Show

Allelic Composition: Prkcdtm1Qxu/Prkcdtm1Qxu
Genetic Background: B6.129P2-Prkcdtm1Qxu

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Prkcdtm1Qxu/Prkcdtm1Qxu
Genetic Background: B6.129P2-Prkcdtm1Qxu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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