ENSMUSG00000027777


Mus musculus

Features
Gene ID: ENSMUSG00000027777
  
Biological name :Schip1
  
Synonyms : P0DPB4 / Schip1 / schwannomin interacting protein 1
  
Possible biological names infered from orthology : P0DPB3
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: E1
Gene start: 68064802
Gene end: 68626481
  
Corresponding Affymetrix probe sets: 10492522 (MoGene1.0st)   1423025_a_at (Mouse Genome 430 2.0 Array)   1437700_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138245
Ensembl peptide - ENSMUSP00000138241
Ensembl peptide - ENSMUSP00000142090
Ensembl peptide - ENSMUSP00000029346
Ensembl peptide - ENSMUSP00000126443
Ensembl peptide - ENSMUSP00000129152
Ensembl peptide - ENSMUSP00000138207
NCBI entrez gene - 30953     See in Manteia.
MGI - MGI:1353557
RefSeq - NM_001113420
RefSeq - NM_001113421
RefSeq - NM_001282044
RefSeq - NM_001282045
RefSeq - NM_013928
RefSeq Peptide - NP_038956
RefSeq Peptide - NP_001106891
RefSeq Peptide - NP_001106892
RefSeq Peptide - NP_001268973
RefSeq Peptide - NP_001268974
swissprot - S4R1J0
swissprot - A0A0A6YXQ5
swissprot - A0A097PIJ2
swissprot - P0DPB4
Ensembl - ENSMUSG00000027777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 schip1ENSDARG00000035175Danio rerio
 ENSGALG00000039468Gallus gallus
 P0DPB3ENSG00000151967Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm21949 / A0A088MLT8 / predicted gene, 21949 / P0DPB3* / SCHIP1* / schwannomin interacting protein 1*ENSMUSG0000010242296


Protein motifs (from Interpro)
Interpro ID Name
 IPR015649  Schwannomin interacting protein 1, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001553 luteinization IGI
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0006807 nitrogen compound metabolic process IMP
 biological_processGO:0008210 estrogen metabolic process IGI
 biological_processGO:0008585 female gonad development IGI
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0010761 fibroblast migration IMP
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IMP
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0048745 smooth muscle tissue development IMP
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060325 face morphogenesis IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0030054 cell junction ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000091 short premaxilla "reduced length of the anterior and interior portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0000097 short maxilla "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0000767 abnormal smooth muscle morphology "anomalous structure of any of the unstriated muscle fibers of the internal organs, blood vessels, hair follicles, etc. " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

 MP:0001121 uterine hypoplasia "reduced size of the uterus due to decreased cell number" [J:45065]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0001126 abnormal ovary morphology "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
Genetic Background: either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6)

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0002136 abnormal kidney physiology "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myo1eGt(ROSA)74Sor/Myo1eGt(ROSA)74Sor,Pdgfrbtm1Sor/Pdgfrb+
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

 MP:0002680 decreased number of corpora lutea "fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004471 short nasal bone "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0005181 decreased circulating estradiol level "less than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0005325 abnormal glomerulus "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

 MP:0005592 abnormal vascular smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0008146 asymmetric rib-sternum attachment "loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0008869 anovulation "complete failure of ovum to be released from an ovarian follicle" [MESH:C13.351.500.056.630.050, MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0009370 decreased thecal cell number "fewer than normal numbers of cells in the sheath of stroma surrounding a secondary ovarian follicle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0009887 abnormal palatal shelf fusion at midline "any anomaly in the process in which the palatal shelves grow toward the midline and adhere along the medial edge epithelia, forming the midline epithelial seam which disappears in later stages" [PMID:16942766]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0009895 decreased palatine shelf size "reduced size of the bony projection of the palatine bone that normally fuses with maxillary shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0011129 decreased secondary ovarian follicle number "fewer than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:csmith]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0011708 decreased fibroblast cell migration "reduced frequency of or less rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0030189 broad snout "increased width of the anterior facial part of the face or muzzle containing the oral and nasal regions" [MGI:anna]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

 MP:0030383 small presphenoid bone "reduced size of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [MGI:anna]
Show

Allelic Composition: Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Genetic Background: involves: 129S4/SvJaeSor

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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