ENSMUSG00000027952


Mus musculus

Features
Gene ID: ENSMUSG00000027952
  
Biological name :Pmvk
  
Synonyms : Phosphomevalonate kinase / Pmvk / Q9D1G2
  
Possible biological names infered from orthology : Q15126
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 89454541
Gene end: 89469013
  
Corresponding Affymetrix probe sets: 10493548 (MoGene1.0st)   1427893_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029564
Ensembl peptide - ENSMUSP00000103033
Ensembl peptide - ENSMUSP00000139116
Ensembl peptide - ENSMUSP00000143154
NCBI entrez gene - 68603     See in Manteia.
MGI - MGI:1915853
RefSeq - NM_001310640
RefSeq - NM_026784
RefSeq - NM_027348
RefSeq Peptide - NP_001297569
RefSeq Peptide - NP_081060
RefSeq Peptide - NP_081624
swissprot - Q9D1G2
swissprot - D3YXP6
Ensembl - ENSMUSG00000027952
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pmvkENSDARG00000070798Danio rerio
 PMVKENSGALG00000046656Gallus gallus
 PMVKENSG00000163344Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005919  Higher eukaryotic phosphomevalonate kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006695 cholesterol biosynthetic process ISO
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway IBA
 biological_processGO:0070723 response to cholesterol IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome IBA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004631 phosphomevalonate kinase activity ISO
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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