| MP:0000519 | hydronephrosis | "dilation of the pelvis and calices of one or both kidneys" [J:56641] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0000522 | cysts in kidney cortex | "abnormal membranous sacs appearing in the renal lobules, tubules and glomeruli" [J:50844] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0000539 | distended urinary bladder | "stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0001426 | polydipsia | "excessive thirst that is relatively prolonged" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0001762 | polyuria | "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0002499 | chronic inflammation | "persistent inflammatory response, often caused by persistent infection or during an autoimmune response" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0002703 | abnormal renal tubules | "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0002705 | dilated renal tubules | "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0002988 | decreased urine osmolarity | "reduction in the concentration of ions in the urine compared to normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:83000] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0003619 | abnormal urine color | "any alteration from the usual straw-coloration of the urine" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0003881 | abnormal nephron morphology | "malformation of the filtering unit of the kidney that includes the renal corpuscle, proximal and distal convoluted tubules, and loop of henle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:71588] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0003985 | renal fibrosis | "formation of fibrous tissue in the kidney as a result of repair or a reactive process" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0004860 | dilated kidney collecting duct | "stretched or widened aperture of the luminal space of the collecting ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0004969 | pale kidney | "kidney lacks normal reddish coloration; often occurs with a bloodless or reduced vasculature condition" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0005325 | abnormal glomerulus | "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0005553 | increased circulating creatinine level | "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0005565 | increased blood urea nitrogen level | "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0008821 | increased blood uric acid level | "greater concentration in the blood of the final oxidation product of purine catabolism in humans and primates, but which in rodents and most other mammals is normally is further oxidized by uricase to allantoin that is excreted in the urine" [MESH:D03.132.960.877, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0009643 | abnormal urine homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uoxin/Uoxin
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0009644 | uremia | "an excess of urea, creatinine, and other nitrogenous end products of protein and amino acid metabolism in the blood; usually indicative of kidney dysfunction" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
| MP:0009645 | crystalluria | "excretion of crystalline material in the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0009810 | increased urine uric acid level | "greater concentration in the urine of the final oxidation product of purine catabolism in humans and primates, but which in rodents and most other mammals is normally is further oxidized by uricase to allantoin that is excreted in the urine" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011346 | renal tubule atrophy | "acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011363 | renal glomerulus atrophy | "acquired diminution of the size of the capillary loops of the kidney associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011402 | renal cast | "any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011405 | tubulointerstitial nephritis | "diffuse or local inflammation and edema of the interstitial tissue of the kidney, including the renal tubules; usually secondary to drug sensitization, systemic infection, graft rejection, or autoimmune disease" [MGI:anna] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011501 | increased glomerular capsule space | "increased volume of the luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries" [MGI:csmith] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
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| MP:0011625 | cystolithiasis | "caliculi, or a solid concretion or crystal aggregation, found in the urinary bladder; often embedded in a glycoprotein matrix which may also contain some nonglycoproteins when associated with infection" [MGI:csmith] |
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Allelic Composition: Lama4tm1Ktry/Lama4tm1Ktry
Genetic Background: B6.129X1-Lama4tm1Ktry
|
