ENSMUSG00000028282


Mus musculus

Features
Gene ID: ENSMUSG00000028282
  
Biological name :Casp8ap2
  
Synonyms : Casp8ap2 / CASP8-associated protein 2 / Q9WUF3
  
Possible biological names infered from orthology : caspase 8 associated protein 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 32615451
Gene end: 32653265
  
Corresponding Affymetrix probe sets: 10503711 (MoGene1.0st)   1449217_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029950
Ensembl peptide - ENSMUSP00000103813
Ensembl peptide - ENSMUSP00000136016
NCBI entrez gene - 26885     See in Manteia.
MGI - MGI:1349399
RefSeq - XM_006537950
RefSeq - NM_001122978
RefSeq - NM_011997
RefSeq - XM_006537949
RefSeq Peptide - NP_036127
RefSeq Peptide - NP_001116450
swissprot - Q9WUF3
swissprot - B1AX75
Ensembl - ENSMUSG00000028282
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casp8ap2ENSDARG00000022718Danio rerio
 CASP8AP2ENSGALG00000015611Gallus gallus
 CASP8AP2ENSG00000118412Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors ISO
 biological_processGO:0036337 Fas signaling pathway ISS
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0016605 PML body ISS
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0003714 transcription corepressor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process IDA
 molecular_functionGO:0032184 SUMO polymer binding ISS
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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