ENSMUSG00000028291


Mus musculus

Features
Gene ID: ENSMUSG00000028291
  
Biological name :Akirin2
  
Synonyms : Akirin2 / B1AXD8
  
Possible biological names infered from orthology : Q53H80
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 34550937
Gene end: 34566908
  
Corresponding Affymetrix probe sets: 10503917 (MoGene1.0st)   1428237_at (Mouse Genome 430 2.0 Array)   1428238_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081322
NCBI entrez gene - 433693     See in Manteia.
MGI - MGI:1889364
RefSeq - NM_001007589
RefSeq - XM_011250060
RefSeq Peptide - NP_001007590
swissprot - B1AXD8
Ensembl - ENSMUSG00000028291
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akirin2ENSDARG00000058729Danio rerio
 AKIRIN2ENSGALG00000015791Gallus gallus
 Q53H80ENSG00000135334Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99LF1 / Akirin1 / Q9H9L7*ENSMUSG0000002307554


Protein motifs (from Interpro)
Interpro ID Name
 IPR024132  Akirin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009792 embryo development ending in birth or egg hatching IMP
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010950 positive regulation of endopeptidase activity IEA
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0032755 positive regulation of interleukin-6 production IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Traddtm1.1Mak/Tradd+
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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