ENSMUSG00000028331


Mus musculus

Features
Gene ID: ENSMUSG00000028331
  
Biological name :Trmo
  
Synonyms : Mus musculus tRNA methyltransferase O (Trmo), transcript variant 2, mRNA. / Q562D6 / Trmo
  
Possible biological names infered from orthology : Q9BU70 / tRNA methyltransferase O
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B1
Gene start: 46376505
Gene end: 46389437
  
Corresponding Affymetrix probe sets: 10512747 (MoGene1.0st)   1452873_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030015
Ensembl peptide - ENSMUSP00000083752
Ensembl peptide - ENSMUSP00000119785
NCBI entrez gene - 74753     See in Manteia.
MGI - MGI:1922003
RefSeq - XM_017320423
RefSeq - NM_001347095
RefSeq - NM_029086
RefSeq - XM_006538325
RefSeq - XM_017320422
RefSeq Peptide - NP_001334024
RefSeq Peptide - NP_083362
swissprot - Q562D6
swissprot - F6QNL9
Ensembl - ENSMUSG00000028331
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trmoENSDARG00000037245Danio rerio
 TRMOENSG00000136932Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR023368  Uncharacterised protein family UPF0066, conserved site
 IPR023370  YaeB-like, N-terminal domain
 IPR036413  YaeB-like superfamily
 IPR036414  YaeB, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation ISO
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016430 tRNA (adenine-N6-)-methyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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