ENSMUSG00000028803


Mus musculus

Features
Gene ID: ENSMUSG00000028803
  
Biological name :Nipal3
  
Synonyms : Nipal3 / NIPA-like protein 3 / Q8BGN5
  
Possible biological names infered from orthology : NIPA like domain containing 3 / Q6P499
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 135445420
Gene end: 135495038
  
Corresponding Affymetrix probe sets: 10517383 (MoGene1.0st)   1429241_at (Mouse Genome 430 2.0 Array)   1434315_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118178
Ensembl peptide - ENSMUSP00000118122
Ensembl peptide - ENSMUSP00000121776
Ensembl peptide - ENSMUSP00000139088
Ensembl peptide - ENSMUSP00000099608
Ensembl peptide - ENSMUSP00000101482
NCBI entrez gene - 74552     See in Manteia.
MGI - MGI:1921802
RefSeq - XM_017320417
RefSeq - NM_028995
RefSeq - XM_006539229
RefSeq - XM_006539230
RefSeq - XM_006539231
RefSeq - XM_006539232
RefSeq Peptide - NP_083271
RefSeq Peptide - NP_001334149
swissprot - A2ADH8
swissprot - A2ADH7
swissprot - A2A987
swissprot - F6V4P1
swissprot - Q8BGN5
Ensembl - ENSMUSG00000028803
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nipal3ENSDARG00000021147Danio rerio
 NIPAL3ENSGALG00000004268Gallus gallus
 NIPAL3ENSG00000001461Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nipal2 / NIPA like domain containing 2 / Q9H841*ENSMUSG0000003887938
Nipal1 / Q8BMW7 / Magnesium transporter NIPA3 / Q6NVV3* / NIPA like domain containing 1*ENSMUSG0000006721920
Nipa2 / Q9JJC8 / Magnesium transporter NIPA2 / Q8N8Q9* / non imprinted in Prader-Willi/Angelman syndrome 2*ENSMUSG0000003045220
Nipal4 / Q8BZF2 / Magnesium transporter NIPA4 / Q0D2K0* / NIPA like domain containing 4*ENSMUSG0000002041119
Nipa1 / Q8BHK1 / Magnesium transporter NIPA1 / Q7RTP0* / non imprinted in Prader-Willi/Angelman syndrome 1*ENSMUSG0000004703717


Protein motifs (from Interpro)
Interpro ID Name
 IPR008521  Magnesium transporter NIPA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002377 immunoglobulin production IMP
 biological_processGO:0015693 magnesium ion transport IEA
 biological_processGO:1903830 magnesium ion transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015095 magnesium ion transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001360 abnormal social investigation "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0001413 abnormal response to new environment "altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0001806 decreased IgM "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0002327 abnormal respiratory function "anomaly in any measure of the processes involved in respiration" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0002495 increased IgA "greater than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0002497 increased IgE "greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0005575 increased pulmonary ventilation "greater than the normal total volume of gas per minute inspired or expired " [RGD:Rat Genome Database submission]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0005585 increased tidal volume "greater than the normal volume of air inspired or expired during each normal respiratory cycle" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

 MP:0008500 increased IgG2a level "greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grid2Lc-J/Grid2+
Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr