Manteia - Molecule gene

ENSMUSG00000028977

Mus musculus

Features

Gene ID:	ENSMUSG00000028977

Biological name :	Casz1

Synonyms :	Casz1 / Q9CWL2 / Zinc finger 1

Possible biological names infered from orthology :	castor zinc finger 1 / Q86V15

Species:	Mus musculus

Chr. number:	4
Strand:	1
Band:	E2
Gene start:	148804429
Gene end:	148954889

Corresponding Affymetrix probe sets:	10510422 (MoGene1.0st) 10510447 (MoGene1.0st) 1442010_at (Mouse Genome 430 2.0 Array) 1446975_at (Mouse Genome 430 2.0 Array) 1453349_at (Mouse Genome 430 2.0 Array) 1459054_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000116095 Ensembl peptide - ENSMUSP00000120307 Ensembl peptide - ENSMUSP00000092035 Ensembl peptide - ENSMUSP00000112978 NCBI entrez gene - 69743 See in Manteia. MGI - MGI:1196251 RefSeq - XM_006539160 RefSeq - NM_001159344 RefSeq - NM_027195 RefSeq - XM_006539157 RefSeq - XM_006539158 RefSeq - XM_006539159 RefSeq Peptide - NP_081471 RefSeq Peptide - NP_001152816 swissprot - B1AS48 swissprot - B1AS47 swissprot - Q9CWL2 swissprot - B1AS46 Ensembl - ENSMUSG00000028977

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
casz1	ENSDARG00000037030	Danio rerio
CASZ1	ENSGALG00000002888	Gallus gallus
CASZ1	ENSG00000130940	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

ID

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR013087	Zinc finger C2H2-type

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006351	transcription, DNA-templated	IBA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0045665	negative regulation of neuron differentiation	IMP
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IEA
biological_process	GO:0060040	retinal bipolar neuron differentiation	IDA
biological_process	GO:0060223	retinal rod cell fate commitment	IMP
biological_process	GO:0060226	negative regulation of retinal cone cell fate commitment	IMP
biological_process	GO:1902870	negative regulation of amacrine cell differentiation	IMP
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000267	abnormal cardiac development	"aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000277	abnormal heart shape	"malformation of the form or the patterning of the heart" [J:18048]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Isl1^tm1(cre)Tmj/Isl1⁺ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000280	thin ventricular wall	"decreased depth of the cardiac wall of the heart ventricles" [J:45302]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0000281	abnormal ventricular septum morphology	"abnormality in the wall between the ventricles of the heart, usually incomplete closure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000292	distended pericardial sacs	"stretched outer parietal layer of the pericardium" [J:25248]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0000295	poorly developed ventricular trabeculae	"retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0001633	poor circulation	"insufficient movement of blood throughout the body" [MGI:cls, J:45302]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0001785	edema	"an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0001879	abnormal lymphatic vessel morphology	"malformation of the network of vessels which carries lymph around the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Trem2^em1Bwef/Trem2⁺ Genetic Background: involves: C57BL/6J * DBA/2J * FVB/N
MP:0001914	hemorrhage	"loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0002128	abnormal blood circulation	"failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Trem2^em1Bwef/Trem2⁺ Genetic Background: involves: C57BL/6J * DBA/2J * FVB/N
MP:0002652	thin myocardial wall	"thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002740	heart hypoplasia	"decreased cell number in the heart" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:77765]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0003920	abnormal right ventricle morphology	"structural anomaly of the right lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Isl1^tm1(cre)Tmj/Isl1⁺ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
MP:0003921	abnormal left ventricle morphology	"structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0004045	abnormal cell cycle checkpoint function	"anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0004056	abnormal myocardial compact layer morphology	"malformation of the outer, dense layer of the myocardium " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004062	dilated right atrium	"an expansion in the volume of the right upper chamber of the heart" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0004090	abnormal sarcomere morphology	"any structural abnormality in the segment of a myofibril between two Z lines comprised of multi-protein complexes composed of three different filament systems; these systems work together to contract and relax muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004091	abnormal Z lines	"any structural abnormality in the cross-striation bisecting the I band of striated muscle myofibrils and serving as the anchoring point of actin filaments at either end of the sarcomere" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004759	decreased mitotic index	"decreased number of cells in G2/M phase" [Bertram_Weiss:Bayer_Schering_Pharma_AG]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Isl1^tm1(cre)Tmj/Isl1⁺ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
MP:0005294	abnormal heart ventricle morphology	"structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0006138	congestive heart failure	"the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0008727	enlarged right atrium	"increased size of the right upper chamber of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0008788	abnormal fetal cardiomyocyte morphology	"any structural anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [PMID:17429040]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010019	liver vascular congestion	"obstruction of the normal flux of blood within the blood vessel network of the liver" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010200	enlarged lymphatic vessel	"increased size of the network of vessels which carries lymph around the body" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010402	ventricular septal defect	"abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010418	perimembraneous ventricular septal defect	"abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0010422	heart right ventricle hypoplasia	"underdevelopment or reduced size of the heart right ventricle, often due to a reduced number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Isl1^tm1(cre)Tmj/Isl1⁺ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
MP:0010500	myocardium hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the heart myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010640	ventricular myocardium compact layer hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the ventricular portion of the outer, dense layer of the myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010725	thin interventricular septum	"decreased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0011099	complete lethality throughout fetal growth and development	"death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Isl1^tm1(cre)Tmj/Isl1⁺ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Cacna1b^{tm1b(KOMP)Wtsi}/Cacna1b^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cacna1b^{tm1b(KOMP)Wtsi}/H
MP:0011390	abnormal fetal cardiomyocyte physiology	"any functional anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [MGI:csmith, PMID:17429040]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0011395	decreased fetal cardiomyocyte proliferation	"reduced ability of the differentiating cardiac muscle cell population to undergo expansion by cell division" [MGI:csmith]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0012269	nuchal edema	"abnormal accumulation of subcutaneous fluid in the nuchal region i.e. at the back of the neck" [MGI:anna]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0012515	abnormal heart apex morphology	"any structural anomaly of the lowest superficial part of the heart, normally directed downward, forward, and to the left, and overlapped by the left lung and pleura; the heart apex is formed by the inferolateral part of the left ventricle and responsible for regulating ventricle contraction" [MGI:anna]	Show Allelic Composition: Casz1^tm1.1Flc/Casz1^tm1.1Flc,Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
MP:0013848	subcutaneous edema	"accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith]	Show Allelic Composition: Casz1^{Gt(CJ0565)Wtsi}/Casz1^{Gt(CJ0565)Wtsi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr