ENSMUSG00000029007


Mus musculus

Features
Gene ID: ENSMUSG00000029007
  
Biological name :Agtrap
  
Synonyms : Agtrap / Q9WVK0 / Type-1 angiotensin II receptor-associated protein
  
Possible biological names infered from orthology : angiotensin II receptor associated protein / Q6RW13
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 148077061
Gene end: 148088031
  
Corresponding Affymetrix probe sets: 10518455 (MoGene1.0st)   1422965_at (Mouse Genome 430 2.0 Array)   1460596_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030865
NCBI entrez gene - 11610     See in Manteia.
MGI - MGI:1339977
RefSeq - XM_017319922
RefSeq - NM_001301281
RefSeq - NM_009642
RefSeq Peptide - NP_033772
RefSeq Peptide - NP_001288210
swissprot - Q9WVK0
Ensembl - ENSMUSG00000029007
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agtrapENSDARG00000077082Danio rerio
 AGTRAPENSGALG00000004623Gallus gallus
 AGTRAPENSG00000177674Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009436  Type-1 angiotensin II receptor-associated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0008217 regulation of blood pressure IMP
 biological_processGO:0038166 angiotensin-activated signaling pathway IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004945 angiotensin type II receptor activity IMP
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001762 polyuria "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

 MP:0004875 increased mean arterial blood pressure "increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

 MP:0006144 increased systolic blood pressure "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

 MP:0009350 decreased urine pH "increased urine acidity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

 MP:0010127 hypervolemia "an abnormally increased amount of space occupied by blood in the vessels" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+,Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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