ENSMUSG00000029036


Mus musculus

Features
Gene ID: ENSMUSG00000029036
  
Biological name :Atad3a
  
Synonyms : Atad3a / ATPase family AAA domain-containing protein 3 / Q925I1
  
Possible biological names infered from orthology : ATAD3B / ATAD3C / ATPase family, AAA domain containing 3A / ATPase family, AAA domain containing 3B / ATPase family, AAA domain containing 3C / Q5T2N8 / Q5T9A4 / Q9NVI7
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 155740641
Gene end: 155761093
  
Corresponding Affymetrix probe sets: 10519183 (MoGene1.0st)   1422461_at (Mouse Genome 430 2.0 Array)   1437343_x_at (Mouse Genome 430 2.0 Array)   1438178_x_at (Mouse Genome 430 2.0 Array)   1456541_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135405
Ensembl peptide - ENSMUSP00000030903
Ensembl peptide - ENSMUSP00000135297
Ensembl peptide - ENSMUSP00000138808
Ensembl peptide - ENSMUSP00000138809
NCBI entrez gene - 108888     See in Manteia.
MGI - MGI:1919214
RefSeq - XM_006538467
RefSeq - NM_179203
RefSeq Peptide - NP_849534
swissprot - H3BK90
swissprot - Q925I1
swissprot - V9GWS5
swissprot - V9GWS6
swissprot - H3BKI6
Ensembl - ENSMUSG00000029036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atad3ENSDARG00000086848Danio rerio
 ENSGALG00000035869Gallus gallus
 ATAD3AENSG00000197785Homo sapiens
 ATAD3BENSG00000160072Homo sapiens
 ATAD3CENSG00000215915Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR021911  ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0001675 abnormal ectoderm development "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0001685 abnormal endoderm development "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0001696 failure to gastrulate "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0001705 abnormal proximal-distal axis patterning "anomaly in the formation or development of a body structure, often a limb, in relation to the structure s proximity to the trunk or point of origin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0001717 absent ectoplacental cone 
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0002084 abnormal developmental patterning "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0002583 absent extraembryonic ectoderm "missing layer of the endoderm of the extraembryonic tissue" [J:40596, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0005028 abnormal trophectoderm "malformed outermost layer of cells in the blastodermic vesicle, which will contact the endometrium and take part in establishing the embryo s means of nutrition" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0005032 abnormal ectoplacental cone 
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0010736 abnormal extraembryonic ectoderm morphology "any structural anomaly of the layer of the ectoderm of the extraembryonic tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Arf4tm1b(KOMP)Wtsi/Arf4tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Arf4tm1b(KOMP)Wtsi/Ucd

 MP:0011189 small embryonic epiblast "reduced size of the tissue derived from the inner cell mass that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper and to the extraembryonic mesoderm" [PMID:21123814]
Show

Allelic Composition: Dpp4tm1Lex/Dpp4tm1Lex
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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