ENSMUSG00000029155


Mus musculus

Features
Gene ID: ENSMUSG00000029155
  
Biological name :Spata18
  
Synonyms : Q0P557 / Spata18 / spermatogenesis associated 18
  
Possible biological names infered from orthology : Q8TC71
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.3
Gene start: 73651379
Gene end: 73679512
  
Corresponding Affymetrix probe sets: 10522445 (MoGene1.0st)   1430351_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109176
Ensembl peptide - ENSMUSP00000137444
Ensembl peptide - ENSMUSP00000040922
Ensembl peptide - ENSMUSP00000064308
NCBI entrez gene - 73472     See in Manteia.
MGI - MGI:1920722
RefSeq - XM_006504155
RefSeq - XM_006504159
RefSeq - XM_006504160
RefSeq - XM_017321119
RefSeq - NM_178387
RefSeq Peptide - NP_848474
swissprot - Q0P557
swissprot - J3QPR5
swissprot - E9Q4M5
swissprot - E9QAP8
Ensembl - ENSMUSG00000029155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q503Q1ENSDARG00000052343Danio rerio
 SPATA18ENSGALG00000013964Gallus gallus
 Q8TC71ENSG00000163071Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026169  Mitochondria-eating protein
 IPR031981  Mitochondria-eating protein, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0033554 cellular response to stress IEA
 biological_processGO:0035694 mitochondrial protein catabolic process IEA
 biological_processGO:0035695 mitophagy by induced vacuole formation IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0002044 colonic adenoma "benign tumors of the large intestine" [J:38772]
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Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0002166 altered tumor susceptibility/resistance "greater than or less than the average number of tumors, usually a specific type, arising in a given strain when compared to controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0002404 intestinal adenoma "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0002957 intestinal adenocarcinoma "malignant neoplasm of epithelial cells in the intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0008011 intestinal polyps "abnormal tissue masses that protrude into the lumen of the intestine and are tethered to the wall of the intestine" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0009309 small intestine adenocarcinoma "malignant neoplasm of epithelial cells in the small intestine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0009314 colon adenocarcinoma "malignant neoplasm of epithelial cells in the colon" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0010273 increased classified tumor incidence "greater than the expected number of tumors with a specific classification type in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18tm1.2Hifa
Genetic Background: involves: C57BL/6J

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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