ENSMUSG00000029276


Mus musculus

Features
Gene ID: ENSMUSG00000029276
  
Biological name :Glmn
  
Synonyms : Glmn / Glomulin / Q8BZM1
  
Possible biological names infered from orthology : glomulin, FKBP associated protein / Q92990
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E5
Gene start: 107548967
Gene end: 107597888
  
Corresponding Affymetrix probe sets: 10532103 (MoGene1.0st)   1418839_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077168
Ensembl peptide - ENSMUSP00000098509
Ensembl peptide - ENSMUSP00000122129
Ensembl peptide - ENSMUSP00000123224
Ensembl peptide - ENSMUSP00000080766
NCBI entrez gene - 170823     See in Manteia.
MGI - MGI:2141180
RefSeq - XM_017320694
RefSeq - NM_001161738
RefSeq - NM_001161739
RefSeq - NM_133248
RefSeq - XM_006534800
RefSeq - XM_011249410
RefSeq Peptide - NP_573511
RefSeq Peptide - NP_001155211
RefSeq Peptide - NP_001155210
swissprot - D3Z0L3
swissprot - Q3T9A5
swissprot - D6RGR3
swissprot - Q8BZM1
Ensembl - ENSMUSG00000029276
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glmnaENSDARG00000058267Danio rerio
 glmnbENSDARG00000010958Danio rerio
 GLMNENSGALG00000005959Gallus gallus
 GLMNENSG00000174842Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013877  YAP-binding/ALF4/Glomulin
 IPR019516  Glomulin/ALF4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0001843 neural tube closure IMP
 biological_processGO:0007166 cell surface receptor signaling pathway ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0040029 regulation of gene expression, epigenetic ISO
 biological_processGO:0042130 negative regulation of T cell proliferation ISS
 biological_processGO:0042327 positive regulation of phosphorylation ISS
 biological_processGO:0042692 muscle cell differentiation ISS
 biological_processGO:0045086 positive regulation of interleukin-2 biosynthetic process ISS
 biological_processGO:0050715 positive regulation of cytokine secretion ISS
 biological_processGO:0072359 circulatory system development IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex ISO
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex ISO
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISO
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005171 hepatocyte growth factor receptor binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0055105 ubiquitin-protein transferase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001701 incomplete embryo turning "arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0001723 disorganized vascular plexus 
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0002621 delayed neural tube closure "delayed fusion of the neuroepithelial layer in early development" [J:79790, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0005312 pericardial effusion "escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

 MP:0011260 abnormal head mesenchyme morphology "any structural anomaly of the primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells" [ISBN:0-683-40008-8]
Show

Allelic Composition: Map2k7tm2.1Rjd/Map2k7tm2.1Rjd
Genetic Background: B6.129S6-Map2k7tm2.1Rjd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr