ENSMUSG00000029282


Mus musculus

Features
Gene ID: ENSMUSG00000029282
  
Biological name :Amtn
  
Synonyms : Amelotin / Amtn / Q9D3J8
  
Possible biological names infered from orthology : Q6UX39
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E1
Gene start: 88376108
Gene end: 88385916
  
Corresponding Affymetrix probe sets: 10522934 (MoGene1.0st)   1453439_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073081
NCBI entrez gene - 71421     See in Manteia.
MGI - MGI:1918671
RefSeq - NM_027793
RefSeq Peptide - NP_082069
swissprot - Q9D3J8
Ensembl - ENSMUSG00000029282
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMTNENSG00000187689Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031501  Amelotin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEP
 biological_processGO:0070169 positive regulation of biomineral tissue development IEA
 biological_processGO:0070175 positive regulation of enamel mineralization IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005605 basal lamina IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002576 abnormal enamel morphology "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ednrbtm1Nrd/Ednrbtm1Nrd,Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J

 MP:0002650 abnormal ameloblast morphology "malformation of the epithelial cells of the inner layer of the enamel organ of the developing tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Ednrbtm1Nrd/Ednrbtm1Nrd,Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J

 MP:0010096 abnormal incisor color "anomaly in the color and shading of the incisor, which normally presents in shades of white" [PMID:12407097]
Show

Allelic Composition: Ednrbtm1Nrd/Ednrbtm1Nrd,Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J

 MP:0030450 abnormal enamel mineralization "anomaly in the process by which calcium salts, mainly carbonated hydroxyapatite, are deposited into the dental enamel" [GO:0070166]
Show

Allelic Composition: Ednrbtm1Nrd/Ednrbtm1Nrd,Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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