ENSMUSG00000029319


Mus musculus

Features
Gene ID: ENSMUSG00000029319
  
Biological name :Coq2
  
Synonyms : 4-hydroxybenzoate polyprenyltransferase, mitochondrial / Coq2 / Q66JT7
  
Possible biological names infered from orthology : coenzyme Q2, polyprenyltransferase / Q96H96
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E4
Gene start: 100654723
Gene end: 100675140
  
Corresponding Affymetrix probe sets: 10531729 (MoGene1.0st)   1452791_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115605
Ensembl peptide - ENSMUSP00000122631
Ensembl peptide - ENSMUSP00000122296
Ensembl peptide - ENSMUSP00000119410
Ensembl peptide - ENSMUSP00000031262
NCBI entrez gene - 71883     See in Manteia.
MGI - MGI:1919133
RefSeq - NM_027978
RefSeq Peptide - NP_082254
swissprot - F7CDY3
swissprot - D6RGA8
swissprot - Q66JT7
swissprot - D3Z296
swissprot - D3YZF3
Ensembl - ENSMUSG00000029319
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 coq2ENSDARG00000059510Danio rerio
 COQ2ENSGALG00000041294Gallus gallus
 COQ2ENSG00000173085Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000537  UbiA prenyltransferase family
 IPR006370  4-hydroxybenzoate polyprenyltransferase
 IPR030470  UbiA prenyltransferase conserved site
 IPR031103  4-hydroxybenzoate octaprenyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006071 glycerol metabolic process IEA
 biological_processGO:0006744 ubiquinone biosynthetic process ISO
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IEA
 molecular_functionGO:0002083 4-hydroxybenzoate decaprenyltransferase activity ISO
 molecular_functionGO:0004659 prenyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
 molecular_functionGO:0047293 4-hydroxybenzoate nonaprenyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Ubiquinol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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