ENSMUSG00000029394


Mus musculus

Features
Gene ID: ENSMUSG00000029394
  
Biological name :Cdk2ap1
  
Synonyms : Cdk2ap1 / Cyclin-dependent kinase 2-associated protein 1 / O35207
  
Possible biological names infered from orthology : O14519
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 124345417
Gene end: 124363082
  
Corresponding Affymetrix probe sets: 10385495 (MoGene1.0st)   10533807 (MoGene1.0st)   1426885_a_at (Mouse Genome 430 2.0 Array)   1435509_x_at (Mouse Genome 430 2.0 Array)   1456314_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143268
Ensembl peptide - ENSMUSP00000031341
Ensembl peptide - ENSMUSP00000107097
Ensembl peptide - ENSMUSP00000107098
Ensembl peptide - ENSMUSP00000107099
NCBI entrez gene - 13445     See in Manteia.
MGI - MGI:1202069
RefSeq - NM_013812
RefSeq Peptide - NP_038840
swissprot - F2Z4B3
swissprot - O35207
Ensembl - ENSMUSG00000029394
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDK2AP1ENSDARG00000115248Danio rerio
 CDK2AP1ENSGALG00000034919Gallus gallus
 O14519ENSG00000111328Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O35207 / Gm12184 / predicted gene 12184 / O14519* / CDK2AP1* / cyclin dependent kinase 2 associated protein 1*ENSMUSG00000078154100
Q9CPY4 / Cdk2ap2 / Cyclin-dependent kinase 2-associated protein 2 / O75956*ENSMUSG0000002485662


Protein motifs (from Interpro)
Interpro ID Name
 IPR017266  Cyclin-dependent kinase 2-associated protein 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0060325 face morphogenesis IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0070182 DNA polymerase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
Show

Allelic Composition: Gna11tm1Soff/Gna11tm1Soff,Gnaqtm2Soff/Gnaqtm2Soff,Tg(Tek-cre/ERT2)1Soff/?
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Cdk2ap1tm1Dtw/Cdk2ap1+
Genetic Background: involves: 129S4/SvJae

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gna11tm1Soff/Gna11tm1Soff,Gnaqtm2Soff/Gnaqtm2Soff,Tg(Tek-cre/ERT2)1Soff/?
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0011106 partial embryonic lethality before somite formation "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Gna11tm1Soff/Gna11tm1Soff,Gnaqtm2Soff/Gnaqtm2Soff,Tg(Tek-cre/ERT2)1Soff/?
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0030046 round forehead "forehead appearance is more circular than usual as viewed from the front" [MGI:anna]
Show

Allelic Composition: Gna11tm1Soff/Gna11tm1Soff,Gnaqtm2Soff/Gnaqtm2Soff,Tg(Tek-cre/ERT2)1Soff/?
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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