ENSMUSG00000029725


Mus musculus

Features
Gene ID: ENSMUSG00000029725
  
Biological name :Ppp1r35
  
Synonyms : Ppp1r35 / Protein phosphatase 1 regulatory subunit 35 / Q9D8C8
  
Possible biological names infered from orthology : Q8TAP8
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 137778849
Gene end: 137780110
  
Corresponding Affymetrix probe sets: 10526687 (MoGene1.0st)   1429255_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031739
Ensembl peptide - ENSMUSP00000114480
Ensembl peptide - ENSMUSP00000143182
NCBI entrez gene - 69871     See in Manteia.
MGI - MGI:1922853
RefSeq - XM_006504615
RefSeq - NM_027242
RefSeq Peptide - NP_081518
swissprot - A0A0G2JFI2
swissprot - Q9D8C8
swissprot - F6XYC5
Ensembl - ENSMUSG00000029725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r35ENSDARG00000068916Danio rerio
 Q8TAP8ENSG00000160813Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029135  Protein phosphatase 1 regulatory subunit 35, C-terminal
 IPR033590  Protein phosphatase 1 regulatory subunit 35


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010923 negative regulation of phosphatase activity ISS
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0019902 phosphatase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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